… Oral direct factor Xa (FXa) inhibitors (rivaroxaban, apixaban, … with all anticoagulants, including
oral FXa inhibitors. There is no … apixaban reference standard (Bristol-Myers Squibb, New …

… of oral direct factor Xa inhibitors when compared directly with dalteparin. The comparative
effectiveness evidence of dalteparin, apixaban, … Within this class, apixaban emerged as the …

… alfa for the reversal of anticoagulation with apixaban and rivaroxaban in life-threatening or
… for coronary or peripheral vascular disease when this indication emerged during the study …

… By inhibition of Factor Xa (FXa) they preclude not only generation of relevant … a new era
of oral anticoagulation. Developed by rational drug design Apixaban and Rivaroxaban inhibit …

… Patients were eligible to participate in the preliminary analysis if they were at least 18
years of age and were reported to have received one of four factor Xa inhibitors — apixaban, …

… Apixaban is an oral factor Xa inhibitor that reversibly and selectively inhibits free and clot
bound factor Xa… Both efficacy and safety are key aspects in the development of new medications…

… , can be a dreaded complication with any factor Xa inhibitors. Although a reversal agent,
andexanet, has been recently approved for apixaban and rivaroxaban, it has several limitations …

… or uncontrolled bleeding with the factor Xa inhibitors apixaban and rivaroxaban. … factor
Xa to bind factor Xa inhibitors, thereby reversing the anticoagulant effects of factor Xa inhibitors…

… Oral factor Xa inhibitors (FXaI) can be administered in fixed doses without the need for …
levels may be useful in guiding decisions for reversal of anticoagulation in emergent settings, …

… Xa activity and thrombin generation and reduced unbound factor Xa inhibitor concentrations
in apixaban… The new oral anticoagulants in clinical practice. Mayo Clin Proc 2013; 88(5): 495…