[HTML][HTML] Mechanistic basis for the differential effects of rivaroxaban and apixaban on global tests of coagulation

PY Kim, CH Yeh, BJ Dale, BA Leslie, AR Stafford… - TH Open, 2018 - thieme-connect.com
… Rivaroxaban and apixaban are oral factor Xa inhibitors that were developed as alternatives
… the Rotochrom chromogenic anti-Xa assay (Diagnostica Stago, Parsippany, New Jersey, …

[HTML][HTML] Using an old test for new tricks: measuring direct oral anti-Xa drug levels by conventional heparin-calibrated anti-Xa assay

CL Maier, WH Asbury, A Duncan… - American journal of …, 2019 - ncbi.nlm.nih.gov
factor Xa decoy protein that rapidly reverses the anticoagulant effects of direct oral factor Xa
inhibitors (FXai) like apixaban and … major bleeding or require emergent surgery. A recent …

A review of oral anticoagulants, old and new, in major bleeding and the need for urgent surgery

TJ Milling Jr, CM Ziebell - Trends in cardiovascular medicine, 2020 - Elsevier
… of Factor Xa inhibitors (FXaIs), currently four drugs: rivaroxaban (Xarelto), apixaban (Eliquis), …
In patients who had received apixaban, the median anti-factor Xa activity decreased from …

Apixaban and rivaroxaban anti-Xa level utilization for guidance of administration of andexanet alfa: a case series

C Morton, A Lista, N Jakowenko, E Salazar… - Journal of Thrombosis …, 2022 - Springer
… andexanet alfa, especially in the absence of time from last dose of oral factor Xa inhibitor. …
concentrations before performing emergent surgical procedures [5]. Gilbert et al. utilized …

[PDF][PDF] New Oral Anticoagulants: An Update.

Q Ahmad, MM Reza, MA Habib, SF Masud… - Journal of Bangladesh …, 2019 - academia.edu
… Dabigatran is a new oral thrombin inhibitor and Rivaroxaban, Apixaban and Edoxaban
are oral factor Xa inhibitors. This review outlines why these new OACs were essential and …

Management of direct factor Xa inhibitor–related major bleeding with prothrombin complex concentrate: a meta-analysis

S Piran, R Khatib, S Schulman, A Majeed… - Blood …, 2019 - ashpublications.org
… The options are limited for reversing the direct oral … agent for anti-factor Xa (anti-FXa)
inhibitors, coagulation factor Xa (… receiving apixaban, betrixaban, edoxaban, and rivaroxaban. …

[HTML][HTML] Evaluation of oral factor Xa inhibitor‐associated extracranial bleeding reversal with andexanet alfa

CJ Nederpelt, L Naar, KW Sylvester, ME Barra… - Journal of Thrombosis …, 2020 - Elsevier
… the degree of oral FXa inhibitor‐exposure in a timely and accurate manner, as the time
since last oral FXa administration is often unknown and apixaban‐ and rivaroxaban‐specific …

[HTML][HTML] Potential therapeutic roles for direct factor Xa inhibitors in coronavirus infections

RA Al-Horani - American Journal of Cardiovascular Drugs, 2020 - Springer
… Importantly, the anti-inflammatory effects of FXa inhibitors … , the anti-inflammatory effects
of rivaroxaban and apixaban … The anti-inflammatory effect of apixaban was also recently …

Andexanet alfa for reversal of factor Xa inhibitors: a critical review of the evidence

J Abdulrehman, JW Eikelboom, DM Siegal - Future Cardiology, 2019 - Future Medicine
… presenting with serious bleeding while receiving apixaban or rivaroxaban. In this review, we
… Some cost reduction may be available through the manufacturer's New Technology Add-On …

A simple and fast HPLC-MS/MS method for simultaneous determination of direct oral anticoagulants apixaban, dabigatran, rivaroxaban in human plasma

J Lagoutte-Renosi, J Le Poupon, A Girard… - … of Chromatography B, 2018 - Elsevier
Oral Anticoagulants (DOACs) represent a group of new oral … The factor Xa inhibitors
apixaban and rivaroxaban have also … Direct factor Xa inhibitors do not influence TT, but have an …