[HTML][HTML] Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
… In a tentative exploration of hospital-treated sepsis data obtained from high-income … via
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
[HTML][HTML] Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis
C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
… to apoptosis in sepsis, thus potentially serving as targets … apoptosis could be a new
therapeutic approach in sepsis. Further, exploring potential therapeutic targets related to apoptosis …
therapeutic approach in sepsis. Further, exploring potential therapeutic targets related to apoptosis …
The pathogenesis and potential therapeutic targets in sepsis
W Zhang, H Jiang, G Wu, P Huang, H Wang, H An… - MedComm, 2023 - Wiley Online Library
… apoptosis in mice during sepsis, suggesting that the ER stress-mediated apoptosis pathway
may be a new target … basis for further exploration of the treatment of sepsis. Here, we review …
may be a new target … basis for further exploration of the treatment of sepsis. Here, we review …
[HTML][HTML] Ferroptosis in sepsis: the mechanism, the role and the therapeutic potential
L Xl, Z Gy, CN - Frontiers in Immunology, 2022 - frontiersin.org
… Ferroptosis is an iron-dependent, non-apoptotic cell death … , etc., and finding potential targets
may offer new prospects for the … In conclusion, the process of exploring the mechanism of …
may offer new prospects for the … In conclusion, the process of exploring the mechanism of …
[HTML][HTML] Potential therapy strategy: targeting mitochondrial dysfunction in sepsis
H Zhang, Y Feng, Y Yao - Military Medical Research, 2018 - Springer
… first observed high rates of apoptosis in splenic lymphocytes and other organs after sepsis,
and inhibition of apoptosis with caspase inhibitors improves survival in sepsis [66, 67]. To …
and inhibition of apoptosis with caspase inhibitors improves survival in sepsis [66, 67]. To …
[HTML][HTML] Long noncoding RNAs: A potential target in sepsis-induced cellular disorder
F Lu, Y Hong, L Liu, N Wei, Y Lin, J He… - Experimental Cell …, 2021 - Elsevier
… inflammatory factor release and T lymphocyte apoptosis in sepsis [61]. As technology …
Since sepsis is defined as organ failure, to further explore the therapeutic targets of lncRNAs…
Since sepsis is defined as organ failure, to further explore the therapeutic targets of lncRNAs…
The potential immunological mechanisms of sepsis
X Zhang, Y Zhang, S Yuan, J Zhang - Frontiers in Immunology, 2024 - frontiersin.org
… -depth exploration of the critical mechanisms underlying sepsis, … DCs could be a promising
therapeutic target for sepsis (41). … apoptosis has been demonstrated to lower sepsis mortality (…
therapeutic target for sepsis (41). … apoptosis has been demonstrated to lower sepsis mortality (…
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
… -induced inflammation, they also have dysfunctional features that impair their antimicrobial
capacities; key findings in sepsis are the delayed apoptosis of neutrophils and the …
capacities; key findings in sepsis are the delayed apoptosis of neutrophils and the …
Therapeutic potential of extracellular vesicles for sepsis treatment
… One such new direction has been the exploration of cell-… [ 43 ] Splenocyte apoptosis in
murine sepsis was also shown to … as a viable therapeutic target for sepsis with the demonstrated …
murine sepsis was also shown to … as a viable therapeutic target for sepsis with the demonstrated …
[HTML][HTML] Nanomaterials targeting macrophages in sepsis: A promising approach for sepsis management
C Song, J Xu, C Gao, W Zhang, X Fang… - Frontiers in …, 2022 - frontiersin.org
… exploring macrophage-based nano-management in sepsis. … In addition, pathogens induce
macrophage apoptosis, pyroptosis, … to achieve macrophage-targeted therapy in sepsis. …
macrophage apoptosis, pyroptosis, … to achieve macrophage-targeted therapy in sepsis. …