Restoring the switch for cancer cell death: Targeting the apoptosis signaling pathway

C Chung - The Bulletin of the American Society of Hospital …, 2018 - academic.oup.com
… Figure 1 provides an overview of the signaling pathways that mediate apoptosis. … to play
an important role in lymphocyte homeostasis. Causative mutations have been identified in the …

[HTML][HTML] Mitochondrial control of lymphocyte homeostasis

YF Yazicioglu, RJ Mitchell, AJ Clarke - Seminars in Cell & Developmental …, 2024 - Elsevier
apoptosis to restore immune homeostasis, with the few survivors differentiating into long-lived
memory T cells. Apoptosis of … Apoptosis is initiated by signalling through either extrinsic or …

The role of Mst1 in lymphocyte homeostasis and function

J Cheng, Y Jing, D Kang, L Yang, J Li, Z Yu… - Frontiers in …, 2018 - frontiersin.org
… discuss the classical signaling pathways orchestrated by the Hippo signaling pathway, and
… /Mst1/2 and lymphocyte homeostasis, adhesion, proliferation, apoptosis, and differentiation …

Altered B lymphocyte homeostasis and functions in systemic sclerosis

A Forestier, T Guerrier, M Jouvray, J Giovannelli… - Autoimmunity …, 2018 - Elsevier
… Then, we analyzed the signaling pathways involved in the … However limited sample collection
added to lymphopenia in … B-cell apoptosis and future studies focusing on B-cell apoptosis

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

T Nakamura, I Naguro, H Ichijo - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
signalling pathways, including mitogen-activated protein kinase (MAPK) signalling pathways
such as the apoptosis signal… of iron homeostasis affects T lymphocyte populations and …

miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways

AS Doghish, AI Abulsoud, SS Elshaer… - … -Research and Practice, 2023 - Elsevier
… program of cell death known as apoptosis, and defective apoptosis is a key factor in …
apoptosis [112]. MiRNAs are one of the crucial macromolecules that control the apoptosis pathway. …

CD95/Fas, non-apoptotic signaling pathways, and kinases

M Le Gallo, A Poissonnier, P Blanco… - Frontiers in …, 2017 - frontiersin.org
… in immune homeostasis and tumor elimination via apoptotic signaling pathways. However, …
(ie, the LNCaP cell line) and evokes apoptosis in activated T lymphocytes (101). In addition to …

[HTML][HTML] Protective effects of selenium against zearalenone-induced apoptosis in chicken spleen lymphocyte via an endoplasmic reticulum stress signaling pathway

Y Xiao, S Xu, S Zhao, K Liu, Z Lu, Z Hou - Cell Stress and Chaperones, 2019 - Elsevier
apoptosis in chicken spleen lymphocyte. In this study, we investigated the underlying
mechanism of the apoptosis induced by ZEN in chicken spleen lymphocyte … -induced apoptosis. …

Splicing factor SRSF1 controls T cell homeostasis and its decreased levels are linked to lymphopenia in systemic lupus erythematosus

T Katsuyama, IJ Martin-Delgado, SM Krishfield… - …, 2020 - academic.oup.com
… Because SRSF1 controls the expression of apoptosis-related genes, we hypothesized
that SRSF1 controls T cell homeostasis and, when reduced, leads to lymphopenia. …

[HTML][HTML] Activation of apoptosis signalling pathways by reactive oxygen species

M Redza-Dutordoir, DA Averill-Bates - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
pathways of apoptosis. The role of ROS in the complex interplay and crosstalk between these
different signalling pathways … to inhibit apoptosis and to regulate ER Ca 2+ homeostasis, …