Aquaporins (AQPs), ordinarily regarded as water channels, have recently been shown to
participate in other cellular functions such as cell-to-cell adhesion, cell migration, cell
proliferation etc. The current investigation was undertaken to find out whether AQP5 water
channel plays a role in corneal epithelial wound healing. Expression of AQP5 in mouse
cornea and transfected Madin-Darby canine kidney (MDCK) cells was detected using
immunofluorescence or EGFP tag. Cell migration and proliferation, the two major events in …