Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?
M Verbelen, ME Weale, CM Lewis - The pharmacogenomics journal, 2017 - nature.com
… to be cost-effective, we assumed that PGx-guided treatment … testing strategy cost-effective
(odds ratio=0.13, P-value <0.05). … for 5 of the 10 drugs covered in this review. Similarly, the cost …
(odds ratio=0.13, P-value <0.05). … for 5 of the 10 drugs covered in this review. Similarly, the cost …
On what basis are medical cost-effectiveness thresholds set? Clashing opinions and an absence of data: a systematic review
… regarding the validity of cost-effective ratios and QALYs may … compensation for the medicines
used to treat Pompe disease … Given the high price of this drug, this example demonstrates …
used to treat Pompe disease … Given the high price of this drug, this example demonstrates …
… the challenge of high-priced prescription drugs in the era of precision medicine: A systematic review of drug life cycles, therapeutic drug markets and regulatory …
… [1;47;48] Though the prices of these drugs were much lower than current new drug price …
drugs as not cost-effective.[148;151] Also, the evidence for the effectiveness of orphan drugs is …
drugs as not cost-effective.[148;151] Also, the evidence for the effectiveness of orphan drugs is …
[HTML][HTML] Systematic review of the evidence on the cost-effectiveness of pharmacogenomics-guided treatment for cardiovascular diseases
… PGx-guided treatment for the drugs clopidogrel and warfarin … PGx-guided clopidogrel
treatment was cost-effective in the … , this study did not specifically examine economic value, but …
treatment was cost-effective in the … , this study did not specifically examine economic value, but …
A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions
CO Plumpton, D Roberts, M Pirmohamed… - Pharmacoeconomics, 2016 - Springer
… to treatment with a number of common drugs. … review has identified tests that are cost effective,
but analyses should be updated and revisited as the evidence base matures and the price …
but analyses should be updated and revisited as the evidence base matures and the price …
[HTML][HTML] Economics and cost-effectiveness of multiple sclerosis therapies in the USA
DM Hartung - Neurotherapeutics, 2017 - Elsevier
… The evidence of how restrictive drug policies or increasing out… annual net price of $58,608
to be considered cost-effective. … drugs, and specifically DMTs, are the single largest medical …
to be considered cost-effective. … drugs, and specifically DMTs, are the single largest medical …
[PDF][PDF] Economics of innovative payment models compared with single pricing of pharmaceuticals
… Whilst we cannot provide evidence of indications that are not being developed … drugs not
being cost-effective even at zero price, eg when used in combination with other costly therapies …
being cost-effective even at zero price, eg when used in combination with other costly therapies …
Cost-effectiveness of biological asthma treatments: a systematic review and recommendations for future economic evaluations
RB McQueen, DN Sheehan, MD Whittington… - …, 2018 - Springer
… was cost-effective only when targeted to specific severe subgroups or given considerable
price … Eight were funded by the manufacturer of omalizumab (Novartis Pharmaceuticals Corp.), …
price … Eight were funded by the manufacturer of omalizumab (Novartis Pharmaceuticals Corp.), …
The value of self-medication: summary of existing evidence
J Noone, CM Blanchette - Journal of medical economics, 2018 - Taylor & Francis
… when a class of drugs becomes available without prescription… improved access to cost-effective
treatment without the need … in this review show that the availability of self-care medicines …
treatment without the need … in this review show that the availability of self-care medicines …
Value-based pricing for emerging gene therapies: the economic case for a higher cost-effectiveness threshold
LP Garrison, T Jackson, D Paul, M Kenston - Journal of managed care & …, 2019 - jmcp.org
… drugs and procedures (Table 1). For example, ICER calculated lifetime cost estimates or
incremental cost-effective … medical care purchases. These additional elements, we would argue, …
incremental cost-effective … medical care purchases. These additional elements, we would argue, …