Asialoglycoprotein receptor and targeting strategies
… To summarize, the exclusive liver expression of ASGP-R presents huge scope in liver-targeted
delivery of small molecules, nucleic acids, and diagnostic agents, which has been amply …
delivery of small molecules, nucleic acids, and diagnostic agents, which has been amply …
Recent advances in asialoglycoprotein receptor and glycyrrhetinic acid receptor-mediated and/or pH-responsive hepatocellular carcinoma-targeted drug delivery
… nm) increased OXA content in the liver and spleen, reduced its content in heart and kidney,
and displayed significant livertargeted delivery [173]. DDS consisting of GA and CTS may …
and displayed significant livertargeted delivery [173]. DDS consisting of GA and CTS may …
[PDF][PDF] Drug targeting strategies for liver cancer and other liver diseases
S Shilpi, R Shivvedi, E Gurnany, S Dixit… - … Drug Des. Dev. Ther, 2018 - academia.edu
… use of monostearin containing solid lipid nanoparticles (SLN) as an effective drug delivery …
,69 and the available targeting ligands such as asialoglycoprotein, lactose and mannose, liver …
,69 and the available targeting ligands such as asialoglycoprotein, lactose and mannose, liver …
A comprehensive review on liver targeting: emphasis on nanotechnology-based molecular targets and receptors mediated approaches
AK Mishra, M Pandey, HK Dewangan, N Sl… - Current Drug …, 2022 - ingentaconnect.com
… , drug delivery carriers, target-specific drug delivery systems, and … receptors include the
asialoglycoprotein receptor (ASGPR), glycyrrhetinic acid receptor (GRAR), glycyrrhizin receptor …
asialoglycoprotein receptor (ASGPR), glycyrrhetinic acid receptor (GRAR), glycyrrhizin receptor …
[PDF][PDF] Variable Asialoglycoprotein-Receptor 1 Expression in Liver Disease: Implications for Therapeutic Intervention
J Huwyler - researchgate.net
… Aim: One of the most promising strategies for the treatment of liver diseases is targeted drug
delivery via the asialoglycoprotein receptor (ASGPR). The success of this approach heavily …
delivery via the asialoglycoprotein receptor (ASGPR). The success of this approach heavily …
Capacity limits of asialoglycoprotein receptor-mediated liver targeting
C Bon, T Hofer, A Bousquet-Mélou, MR Davies… - MAbs, 2017 - Taylor & Francis
… To investigate the in-vivo drug delivery capacity of the ASGPR, we aimed to exploit the
target-mediated drug disposition (TMDD) of a newly developed anti-ASGPR antibody (ASGPR Ab…
target-mediated drug disposition (TMDD) of a newly developed anti-ASGPR antibody (ASGPR Ab…
Herbal and polymeric approaches for liver-targeting drug delivery: novel strategies and their significance
… carcinoma targeting due to its high affinity for asialoglycoprotein receptor. … few delivery
systems are marketed as liver targeted drug delivery system. In future, liver-targeted drug delivery …
systems are marketed as liver targeted drug delivery system. In future, liver-targeted drug delivery …
Development of liver cell-targeted drug delivery systems: experimental approaches
YA Ivanenkov, SY Maklakova… - Russian Chemical …, 2017 - iopscience.iop.org
… An active liver-targeted drug delivery system based on GA-modified SCTS micelles (GA-SCTS)
showed a relatively high in vivo efficacy. Using a GA-SCTS-fluorescein isothiocyanate …
showed a relatively high in vivo efficacy. Using a GA-SCTS-fluorescein isothiocyanate …
Asialoglycoprotein Receptor‐Targeted Superparamagnetic Perfluorooctylbromide Nanoparticles
Y Li, CF Yang, H Zuo, A Li, SK Das… - Contrast Media & …, 2021 - Wiley Online Library
… serve as a liver-targeted contrast agent for MR receptor imaging. … and drug delivery. The
perfluorocarbon (PFC) nanoparticle is a unique platform technology which may be applied to …
perfluorocarbon (PFC) nanoparticle is a unique platform technology which may be applied to …
Asialoglycoprotein receptor targeted optical and magnetic resonance imaging and therapy of liver fibrosis using pullulan stabilized multi-functional iron oxide …
… Overall, the developed P-SPIONs might serve as an excellent hepatocyte specific MR contrast
agent and PSPION-AT as a liver targeted fluorescent probe for the early diagnosis of liver …
agent and PSPION-AT as a liver targeted fluorescent probe for the early diagnosis of liver …