… Leprosy presents a strong link with the host genetic background. The most significant
susceptibility factors are located in the MHC … with leprosy phenotypes (rev in [1]). Genome-wide …

… failure to find genetic associations between rs1800629 and leprosy phenotypes in our
population… , and others in close linkage disequilibrium with it, in regulating TNF expression during …

… that leprosy phenotypes are largely dependent on the genetic … Later, linkage and association
analysis, first applied to the … coding for cytokines such as TNFA (tumor necrosis factor alpha…

… The strong link between leprosy and the host genetic … By far the most significant genetic
association with leprosy per se has … with leprosy phenotypes by candidate gene approaches, …

… high genetic heterogeneity and distinctive patterns of linkage … final phenotype in patients
with leprosy. Accurate profiling of … No association of polymorphisms in the tumor necrosis factor …

… Although the phenotype of susceptibility to infection by M. … ), and TNFA (A, G) and leprosy
when performed a linkage study … Tumor necrosis factor promoter polymorphism (TNF2) seems …

… expression of cathelicidin and tumor necrosis factor (TNF)-α. … Th2 phenotype, was also found
to be a leprosy susceptibility … found to be leprosy-associated by both linkage analysis and …

… reported in linkage of association with leprosy phenotypes. … of the IL10 gene in leprosy
phenotypes confirmed the association of the TSS … class II and tumour necrosis factor genes. …

… of leprosy with selected genes impacting on its phenotypes. … In the MHC class-III region,
linkage disequilibrium mapping of … 80) as a risk factor for infection: association was reported in a …

… of linkage disequilibrium (LD) across the entire HLA locus [9]. … the association between
leprosy and HLA class I and class II … -C loci with leprosy phenotypes [9]. However, till date, no …