Association between subclinical hypothyroidism and metabolic syndrome among individuals with depression
MD Kim, HJ Yang, NR Kang, JH Park… - Journal of affective …, 2020 - Elsevier
MD Kim, HJ Yang, NR Kang, JH Park, YE Jung
Journal of affective disorders, 2020•ElsevierAbstracts Background Although the connection among low thyroid function, metabolic
abnormalities, and depression is well documented, the relationship between subclinical
hypothyroidism (SCH) and metabolic syndrome (MetS) in depression remains unclear. This
study examined the association between SCH and MetS in a large sample with depression.
Methods The study analyzed 370 individuals with depression who participated in the 2014
Korea National Health and Nutrition Examination Survey. Associations between the …
abnormalities, and depression is well documented, the relationship between subclinical
hypothyroidism (SCH) and metabolic syndrome (MetS) in depression remains unclear. This
study examined the association between SCH and MetS in a large sample with depression.
Methods The study analyzed 370 individuals with depression who participated in the 2014
Korea National Health and Nutrition Examination Survey. Associations between the …
Abstracts
Background
Although the connection among low thyroid function, metabolic abnormalities, and depression is well documented, the relationship between subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) in depression remains unclear. This study examined the association between SCH and MetS in a large sample with depression.
Methods
The study analyzed 370 individuals with depression who participated in the 2014 Korea National Health and Nutrition Examination Survey. Associations between the presence of SCH and MetS were estimated after adjusting for related factors using multivariate logistic regression analysis.
Results
In the 370 individuals with depression, the prevalence of SCH was 9.4% (SE = 1.6%). The prevalence of MetS was significantly higher in depressed individuals with than in those without SCH (56.3 ± 9.5% vs. 22.8 ± 2.6%; p = 0.001). After adjusting for covariates, the odds of having MetS were 7.127 times greater among depressed individuals with SCH than among those without SCH (95% confidence interval, 2.077–24.458).
Limitations
The cross-sectional study design prevented inferences regarding causality and the effects of changes in variables.
Conclusions
Depressed individuals with SCH are more likely to meet the criteria for MetS. These results highlight the significance of low thyroid function and the metabolic burden of individuals with depression.
Elsevier
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