… and eotaxins were found in induced sputum from patients experiencing acute asthma
exacerbations (… Binding interactions of human interleukin 5 with its receptor α subunit. Large scale …

… for severe asthma (Table 1) In our analysis, approximately 25% of patients with severe asthma
… We classified the patients with severe asthma (n ¼ 102) into four phenotypes based on …

… society/american thoracic society (ERS/ATS) consensus, severe asthma is defined as asthma
that … Interleukin-5 (IL-5) is essential for eosinophil terminal differentiation, maturation and …

… neutrophils contribute to the development of severe asthma or asthma exacerbation. IL-8,
which … expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with …

… Interleukin-5 acts on eosinophils at multiple functional levels … with chemotactic factors such
as eotaxin-1 (CCL11) to attract … surgery and a frequent association with severe asthma (60). …

… , and immunological parameters of asthmatic children in interleukin-5 levels Further, in this
study, there was a significant difference in the IL-5 level in asthma patients depending on sex, …

… is insufficient, the anti-interleukin-5 antibody mepolizumab can be … mediator of allergic
asthma and induces IL-5 and eotaxin/CCL11 … These associations led to the speculation that the …

… stem cells and specialized CD34 + interleukin-5 receptor (IL-5R… single eotaxin-1 or eotaxin-2
KO mice and both eotaxin 1 and … European Respiratory Society/American Thoracic Society (…

… It is clinically important to underline that eotaxin-1 cannot mobilize … since eotaxin-1 alone
can only lead to blood eosinophilia but not to tissue infiltration. On the contrary, blocking eotaxin…

… Expression of chemokine receptors in eosinophils and interleukin-5 levels in patients was not
… No significant difference was detected in eotaxin concentrations in EA, although eotaxin-2 …