Interaction of hypericin with guanine-rich DNA: Preferential binding to parallel G-Quadruplexes

X Zhang, B Jin, W Zheng, N Zhang, X Liu, T Bing… - Dyes and …, 2016 - Elsevier
… In this paper, we studied the interaction of Hyp with different DNA forms. Hyp was found
to selectively bind parallel DNA G-Quadruplexes (G4) over other DNA forms, such as ss-/ds-DNA

An increase in DNA G-quadruplex formation in acute myelocytic leukemia is detected by a supramolecular probe

H Chen, X Guo, X Li, Y Tang, H Sun - Spectrochimica Acta Part A …, 2021 - Elsevier
quadruplex structures in physiological buffer solution, chromosomes, and cells. Using this
probe, we tested the DNA … G-quadruplex by the supramolecular probe of the cyanine dye MTC …

… modification of nonspecific thiazole orange for ligand-DNA interaction study: Understanding the ligand recognition selectivity towards G4-DNA over duplex-DNA

Y Zhu, J Hou, XH Huang, DX Zhong, W Long… - Journal of …, 2020 - Elsevier
… binding ligands derived from nonspecific thiazole orange dye… as G-quadruplexes versus
double-stranded DNA is important … of G4-DNA targeting fluorescent probes have been reported …

Development of squaraine based G-quadruplex ligands using click chemistry

X Zhang, Y Wei, T Bing, X Liu, N Zhang, J Wang… - Scientific Reports, 2017 - nature.com
The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in
gene expression. To this end, the development of new G4 ligands has attracted extensive …

Advancing small ligands targeting RNA for better binding affinity and specificity: A study of structural influence through molecular design approach

C Wang, YJ Lu, SY Cai, W Long, YY Zheng… - Sensors and Actuators B …, 2018 - Elsevier
… We therefore designed two new analog molecules as the RNA-specific fluorescent probes,
… a standard DNA-staining dye DAPI for simultaneously imaging or mapping of RNA and DNA

Interaction analysis of RNA G-quadruplex with ligands and in situ imaging application

L Jiang, J Teng, X Liu, L Xu, T Yang, X Hu, S Ding… - Analytical …, 2024 - Elsevier
… mechanisms of RNA G4 and DNA G4 in the interaction with ligands, … DNA G4/hemin, RNA
G4/ThT fluorescence system exhibited a significant improvement (2∼3-fold) compared to DNA

Fluorescent Modified Nucleosides and Their Impact on Structure and Function of a Model Aptamer

A Van Riesen - 2016 - atrium.lib.uoguelph.ca
… CDs of DNA arise from the asymmetric backbone sugars and the … spectra of B-form DNA and
quadruplex DNA allows for easy … use as fluorescent probes in comparison to internal probes.…

Combinatorial chemistry approaches for the development of G-quadruplex DNA and RNA ligands

O Reznichenko - 2021 - theses.hal.science
… PDC scaffold was also used for the development of fluorescent probes. For example, the …
dyes, distyrylpyridinium dyes etc.).Most of ligands that bind to telomeric hybrid G-quadruplexes

Elucidating the cation-dependent folding of DNA G-quadruplexes, and how to target specific topologies with synthetic ligands

A König - 2023 - theses.hal.science
… Beyond generic fluorescence dyes such as thiazole orange … as G-quadruplex specific
fluorescent probes.Some notable G-… One asymmetric unit shown in green, the other one in red. …

Insight into RNA G-Quadruplex/Ligand Complex: The Interaction Mechanism and Application in Biosensing

J Teng, L Jiang, X Liu, L Xu, T Yang, X Hu… - Ligand Complex: The … - papers.ssrn.com
… Then, we performed fluorescence kinetics experiment of binding affinity for DNA 321 …
Asymmetric distyrylpyridinium dyes as red-emitting fluorescent probes for …