Left-right asymmetry in heart development and disease: forming the right loop
A Desgrange, JF Le Garrec, SM Meilhac - Development, 2018 - journals.biologists.com
… sudden sideways deformation. It applies to the growth of the … that may contribute to a
heart-specific generator of asymmetry … small left-right asymmetries at the poles of the heart are …
heart-specific generator of asymmetry … small left-right asymmetries at the poles of the heart are …
Epithelial properties of the second heart field
… the SHF, resulting in reduced SHF contributions to both poles of the … of SHF cells concerns
left–right differences, evident from … Asymmetrical cell behavior in the gut mesentery has been …
left–right differences, evident from … Asymmetrical cell behavior in the gut mesentery has been …
First and second heart field
M Buckingham - Congenital Heart Diseases: The Broken Heart: Clinical …, 2016 - Springer
… contribution of the first heart field (FHF – red), located in the … for the establishment of left/right
asymmetry in the embryo and … SHF contribution to the poles of the heart, since earlier effects …
asymmetry in the embryo and … SHF contribution to the poles of the heart, since earlier effects …
[PDF][PDF] Transient nodal signaling in left precursors coordinates opposed asymmetries shaping the heart loop
A Desgrange, JF Le Garrec, S Bernheim… - Developmental Cell, 2020 - cell.com
… Our results show that the generator of asymmetry is … the left-right patterning of the heart poles
correlates with the … in the right second heart field, as well as the asymmetric contribution of …
correlates with the … in the right second heart field, as well as the asymmetric contribution of …
A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics
JF Le Garrec, JN Domínguez, A Desgrange… - Elife, 2017 - elifesciences.org
… of the heart and contribute to heart anomalies in children. … ingression from the posterior
second heart field. Symmetrical … we first observed left-right asymmetry at the arterial pole. After …
second heart field. Symmetrical … we first observed left-right asymmetry at the arterial pole. After …
T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field
C De Bono, C Thellier, N Bertrand… - Human molecular …, 2018 - academic.oup.com
… Our results are consistent with fate mapping experiments in avian … Asymmetric fate of the
posterior part of the second heart field results in unexpected left/right contributions to both poles …
posterior part of the second heart field results in unexpected left/right contributions to both poles …
[HTML][HTML] Anterior lateral plate mesoderm gives rise to multiple tissues and requires tbx5a function in left-right asymmetry, migration dynamics, and cell specification of …
LMF Mao, EATB Anderson, RK Ho - Developmental biology, 2021 - Elsevier
… asymmetrical contributions of lateral aLPM-derived heart … and arterial poles are called the
Second Heart Field (SHF). … unintended photoconversions did not contribute to the heart as …
Second Heart Field (SHF). … unintended photoconversions did not contribute to the heart as …
The heart field transcriptional landscape at single-cell resolution
RG Kelly - Developmental Cell, 2023 - cell.com
… the second heart field (SHF), contribute progressively during looping morphogenesis to the
right ventricle and outflow tract at the arterial pole of the heart… left-right expression results from …
right ventricle and outflow tract at the arterial pole of the heart… left-right expression results from …
The deployment of cell lineages that form the mammalian heart
SM Meilhac, ME Buckingham - Nature Reviews Cardiology, 2018 - nature.com
… a given type that contribute to different parts of the heart. The … to the venous pole move
anteriorly to contribute to the … , along the anterior–posterior axis and along the left–right axis, with …
anteriorly to contribute to the … , along the anterior–posterior axis and along the left–right axis, with …
A right-handed signalling pathway drives heart looping in vertebrates
… hinders the observation of multiple internal left–right (L/R) … that contribute to the pericardium
and the posterior pole 14,15 … Here we show an asymmetric L/R EMT process that drives …
and the posterior pole 14,15 … Here we show an asymmetric L/R EMT process that drives …