Left-right asymmetry in heart development and disease: forming the right loop

A Desgrange, JF Le Garrec, SM Meilhac - Development, 2018 - journals.biologists.com
sudden sideways deformation. It applies to the growth of the … that may contribute to a
heart-specific generator of asymmetry … small left-right asymmetries at the poles of the heart are …

First and second heart field

M Buckingham - Congenital Heart Diseases: The Broken Heart: Clinical …, 2016 - Springer
contribution of the first heart field (FHF – red), located in the … for the establishment of left/right
asymmetry in the embryo and … SHF contribution to the poles of the heart, since earlier effects

Epithelial properties of the second heart field

C Cortes, A Francou, C De Bono, RG Kelly - Circulation research, 2018 - Am Heart Assoc
… the SHF, resulting in reduced SHF contributions to both poles of the … of SHF cells concerns
leftright differences, evident from … Asymmetrical cell behavior in the gut mesentery has been …

[HTML][HTML] Current perspectives in cardiac laterality

M Campione, D Franco - Journal of Cardiovascular Development and …, 2016 - mdpi.com
… of cardiac looping and laterality, and discuss the contribution of … both the morphology
of the SA region and the asymmetric … In this context, it is important to highlight that the leftright

Nkx genes establish second heart field cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression

S Colombo, C de Sena-Tomás, V George… - …, 2018 - journals.biologists.com
… We found that our results from the EdU incorporation assay … precursor population contributing
to the arterial pole (Fig. 3F). … cell fate by Nkx genes in the SV during cardiac development. …

From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies leftright patterning

G McDowell, S Rajadurai… - … Transactions of the …, 2016 - royalsocietypublishing.org
… , and individual cells can contribute to mechanical differences in … While not surprising given
regulative development as a … mRNA injections were made into the animal pole of eggs within …

The heart field transcriptional landscape at single-cell resolution

RG Kelly - Developmental Cell, 2023 - cell.com
… the second heart field (SHF), contribute progressively during looping morphogenesis to the
right ventricle and outflow tract at the arterial pole of the heartleft-right expression results from …

T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field

C De Bono, C Thellier, N Bertrand… - Human molecular …, 2018 - academic.oup.com
… Our results are consistent with fate mapping experiments in avian … Asymmetric fate of the
posterior part of the second heart field results in unexpected left/right contributions to both poles

Shaping the mouse heart tube from the second heart field epithelium

P Palmquist-Gomes, SM Meilhac - Current Opinion in Genetics & …, 2022 - Elsevier
… Finally, the poles of the heart undergo asymmetric movements … These processes altogether
contribute to the left-rightresults in unexpected left/right contributions to both poles of …

Investigation of mechanisms regulating second heart field progenitor cell addition to alternate poles of the mouse heart and the regulation of myogenic fate in …

C De Bono - 2017 - theses.fr
… the contribution of SHF cells to alternate cardiac poles. In … results in atrioventricular septal
defects. Using genetic lineage … on the leftright axis as well as the anterior-posterior axis. …