… and elongates especially toward the anterior pole (Figure 1C). The … Our results argue in
favor of a crucial role of competence in the … rerio can uncover unexpected levels of regulation. …

… sign of morphological left–right asymmetry and soon … second heart field (SHF) that is medially
located and will subsequently contribute to both the arterial and venous poles of the heart […

… demonstrating a left-right asymmetry observable at the poles. … factors that contributed to the
bending of the heart, including … anterior region of the tube to explain the left-right asymmetry …

… arterial pole is known as the anterior SHF or secondary heart field … Asymmetric fate of the
posterior part of the second heart field results in unexpected left/right contributions to both poles …

… ) enable the contributions of the left/right second heart field to be … the arterial and venous
poles of the heart is consistent with … the facts that left/right asymmetry is regulated independently …

… both in cardiogenesis and in left/right body asymmetry (Nodal, … myocardial precursors are
asymmetrically contributing to the … between the venous pole and part of the arterial pole, which …

… the region that will eventually contribute cells to the heart tube [18… parts of the cardiac venous
pole develop from the second … is required for normal left-right asymmetry in vertebrates. Nat …

… However, it remains enigmatic how atrial left-right asymmetry … -posterior fields without
contribution from the second heart … venous pole, the second heart field contributes cells to both …

… and Nodal are important in left–right asymmetry [17] while … In normal embryos the OFT
septal complex has contributed to a … on the role of TGFß signaling in the arterial pole is wanted. …

… have noted, to our surprise, that the contributions of the CJ to … , is formed within the two heart
fields shortly before the latter … well as arterial poles of the single median heart tube, thereby …