Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events
S Ajeganova, MLE Andersson, J Frostegård… - Arthritis Research & …, 2021 - Springer
… We hypothesized that the association between IgM anti-PC and the risk of CV outcome is
different in the presence of CV risk factors. We therefore further performed analyses within the …
different in the presence of CV risk factors. We therefore further performed analyses within the …
… against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome
EC Knudsen, I Seljeflot, TA Aksnes, J Eritsland… - Plos one, 2019 - journals.plos.org
… and coronary occlusion is the leading underlying cause of myocardial infarction and sudden
cardiac … Autoantibodies directed towards a variety of oxidation-specific epitopes or self—…
cardiac … Autoantibodies directed towards a variety of oxidation-specific epitopes or self—…
A role for autoantibodies in atherogenesis
… autoantibody (highest vs. lowest quartiles of autoantibody titer) on cardiovascular outcomes.
… the association between anti phosphorylcholine autoantibodies (anti-PC)- and CVD-related …
… the association between anti phosphorylcholine autoantibodies (anti-PC)- and CVD-related …
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation
J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… could be related to the complexity of the LDL-oxidation process where antigens exposed
could vary to some extent, and there may also be differences in methods used for antibody …
could vary to some extent, and there may also be differences in methods used for antibody …
Immunoglobulin A antibodies against phosphorylcholine in rheumatoid arthritis patients and its association with clinical outcomes
A Syed - 2021 - diva-portal.org
… with the clinical outcomes. Potential immunomodulatory … antibody to target the root
causes of the inflammation and treat patients with early RA, thereby atherosclerosis and CVD…
causes of the inflammation and treat patients with early RA, thereby atherosclerosis and CVD…
IgA antibodies to phosphocholine associate with long-term cardiovascular disease risk
… The present study highlights the potential of IgA antibody measurements to phosphocholine
as a new marker in CVD risk assessment and calls for additional studies on larger well-…
as a new marker in CVD risk assessment and calls for additional studies on larger well-…
Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality
… We also divided patients into inflamed C-reactive protein (CRP) > 5·6 mg/ml and non-inflamed
CRP. Antibody levels were determined by in-house enzyme-linked immunosorbent assay. …
CRP. Antibody levels were determined by in-house enzyme-linked immunosorbent assay. …
Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases
J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death in …
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death in …
IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases
… The antibody levels were used for cases vs controls and cross-disease analysis. Statistical …
for each antibody. The correlation between antibody level and cardiovascular score (CV) was …
for each antibody. The correlation between antibody level and cardiovascular score (CV) was …
Non-linear relationship between anti-apolipoprotein A-1 IgGs and cardiovascular outcomes in patients with acute coronary syndromes
N Vuilleumier, S Pagano, C Combescure… - Journal of clinical …, 2019 - mdpi.com
… Because experimental evidence indicates that these autoantibodies could per se promote …
fact that we did not assess other auto-antibodies of potential CV relevance, which is outside of …
fact that we did not assess other auto-antibodies of potential CV relevance, which is outside of …