Organoid and spheroid tumor models: Techniques and applications
S Gunti, ATK Hoke, KP Vu, NR London Jr - Cancers, 2021 - mdpi.com
… Organoids and spheroids are different 3D cell culture models … such applications as cancer
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
Role of microenvironment in glioma invasion: what we learned from in vitro models
I Manini, F Caponnetto, A Bartolini, T Ius… - International journal of …, 2018 - mdpi.com
… by a phenomenon referred to as autologous chemotaxis [58]. … directional migration of tumour
cells from the spheroid mass [134,… a glioma culture or from dissociated brain tumours—and …
cells from the spheroid mass [134,… a glioma culture or from dissociated brain tumours—and …
Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties
… and represents the most common primary malignant brain tumor in adults with a median
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
Modelling Metastasis in Neuroblastoma: 3D Culture Assays of Local Tumour Invasion
C Gavin - 2022 - repository.rcsi.com
… culture and 3D invasion assays as a valuable tool to discover the molecular mechanisms
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
Modeling human brain tumors and the microenvironment using induced pluripotent stem cells
… To more accurately model the human brain, a 3D culture … derived GSC spheroids exhibited
different invasion potential that … cells, this forms the basis for establishing autologous invasion …
different invasion potential that … cells, this forms the basis for establishing autologous invasion …
Developing bioinspired three-dimensional models of brain cancer to evaluate tumor-homing neural stem cell therapy
… tissue culture hood and incubated overnight in 3D cell culture … when designing redosing
studies and tracking tumor invasion. … In the case of autologous NSC-based therapies, a method …
studies and tracking tumor invasion. … In the case of autologous NSC-based therapies, a method …
[HTML][HTML] Glioblastoma organoids: pre-clinical applications and challenges in the context of immunotherapy
… For Glioblastoma (GBM), the most severe form of brain cancer … termed ‘organotypic tumor
spheroids’, these cultures fulfill the … vivo co-cultures of organoids with autologous PBMCs have …
spheroids’, these cultures fulfill the … vivo co-cultures of organoids with autologous PBMCs have …
GD2 CAR T cells against human glioblastoma
M Prapa, C Chiavelli, G Golinelli, G Grisendi… - NPJ precision …, 2021 - nature.com
… on the delivery route for targeting brain tumors, we compared … C6) co-cultures with either
autologous or allogeneic GD2 … we used a biocompatible 3D cell culture device that allows a …
autologous or allogeneic GD2 … we used a biocompatible 3D cell culture device that allows a …
[HTML][HTML] Is it time to start transitioning from 2D to 3D cell culture?
… Hydrophilic glass fibers are important for modeling 3D tumors testing antibodies, invasion,
as well as tracking cell migration. SeedEZ discovered by Lena Biosciences is such an inert …
as well as tracking cell migration. SeedEZ discovered by Lena Biosciences is such an inert …
Three-dimensional cell cultures in drug discovery and development
Y Fang, RM Eglen - Slas discovery: Advancing Life Sciences …, 2017 - journals.sagepub.com
… In this review, we assess leading 3D cell culture … increased the invasion rate of HCT116
cells in spheroid through 3D … engineered a human bladder by isolating autologous bladder …
cells in spheroid through 3D … engineered a human bladder by isolating autologous bladder …