[HTML][HTML] Ultrasonic surgical aspirate is a reliable source for culturing glioblastoma stem cells

J Behnan, B Stangeland, T Langella, G Finocchiaro… - Scientific reports, 2016 - nature.com
… by identifying three different brain tumor types within a single … samples in an organotypic
spheroid culture system is unlikely … Therapeutic vaccination against autologous cancer stem …

[HTML][HTML] 3D tumor spheroid and organoid to model tumor microenvironment for cancer immunotherapy

Y Zhu, E Kang, M Wilson, T Basso, E Chen, Y Yu, YR Li - Organoids, 2022 - mdpi.com
… , and are able to aid invasion in scaffold-based cultures by “leading” tumor cells through the
… -T cells could be generated from autologous leukocytes, mimicking the clinical applications …

Recapitulating the Microenvironment of Glioblastoma Multiforme Using 3D Tissue Culture Models

M Logun, S Stice, L Karumbaiah - Engineering 3D Tissue Test …, 2017 - taylorfrancis.com
… Eventually, brain tumors outgrow the limited space in the brain and … De novo brain tumors
invade diffusely as single … in 2D cultures than with tumor spheroid cultures assuming equal …

[HTML][HTML] Modeling human brain tumors and the microenvironment using induced pluripotent stem cells

ZI Khamis, DB Sarker, Y Xue, N Al-Akkary, VD James… - Cancers, 2023 - mdpi.com
… To more accurately model the human brain, a 3D culture … derived GSC spheroids exhibited
different invasion potential that … cells, this forms the basis for establishing autologous invasion

[HTML][HTML] Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling

Z Abou-Mrad, JB Gharios, MM Moubarak… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
… to serve as screening tools for studying brain tumor growth and … hepatocellular carcinoma
spheroids in which a 3D co-culture … Cytolytic effects of autologous lymphokine-activated killer …

Hydrogel microenvironments for cancer spheroid growth and drug screening

Y Li, E Kumacheva - Science advances, 2018 - science.org
… 15) are commonly used for 3D cancer cell culture owing to their specific biophysical and cell…
, the mechanism of cancer invasion was not studied in detail. Cancer cell invasion was also …

[HTML][HTML] Cancer Spheroids Embedded in Tissue-Engineered Skin Substitutes: A New Method to Study Tumorigenicity In Vivo

MA Barbier, K Ferland, H De Koninck… - International Journal of …, 2024 - mdpi.com
… native human skin that can be produced from autologous cells … proliferating melanoma cells
which invade the dermo–epidermal … cells may not react well or be able to grow in our culture

[HTML][HTML] Tumor spheroids under perfusion within a 3D microfluidic platform reveal critical roles of cell-cell adhesion in tumor invasion

YL Huang, Y Ma, C Wu, C Shiau, JE Segall, M Wu - Scientific reports, 2020 - nature.com
… can influence brain tumor cell invasion via both autologous … co-culture tumor spheroid assay
where tumor spheroids were … within tumor spheroids in the context of tumor invasion. We …

The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma

M Wong, S Vasani, O Breik, X Zhang, L Kenny… - Cancer …, 2024 - Wiley Online Library
Spheroids are simple 3D cell cultures that result in spherical … and subsequent tumour
angiogenesis in tumoroid co-cultures. … co-culture of tumoroids with autologous clonally expanded …

[HTML][HTML] 3D tumor models and their use for the testing of immunotherapies

N Boucherit, L Gorvel, D Olive - Frontiers in immunology, 2020 - frontiersin.org
… 3-D culture methods such as spheroids and organoids, which … tumor invaded tissue or at a
distant site such as tumor-cell … in the presence of autologous circulating lymphocytes and IFN-…