Immune-inflammatory responses in atherosclerosis: role of an adaptive immunity mainly driven by T and B cells
DA Chistiakov, AN Orekhov, YV Bobryshev - Immunobiology, 2016 - Elsevier
… Humoral immunity is mediated by B cells that release antigen-specific … of T and B lymphocytes
in atherosclerosis on the basis of studies in humans and animal models of atherosclerosis. …
in atherosclerosis on the basis of studies in humans and animal models of atherosclerosis. …
Immunity in atherosclerosis: focusing on T and B cells
AV Poznyak, EE Bezsonov, TV Popkova… - International Journal of …, 2021 - mdpi.com
… secrete poorly specific natural IgM antibodies, creating a rapid and T-cell-independent
humoral response. Secreted B1 antibodies are polyreactive and are the main defense against …
humoral response. Secreted B1 antibodies are polyreactive and are the main defense against …
The role of B cells in atherosclerosis
AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
… , IgG, and IgE as well as regulation of T cell responses affecting the progression of this disease,
… the spectrum of B cell involvement in dyslipidaemia and atherosclerosis. B cell receptors: …
… the spectrum of B cell involvement in dyslipidaemia and atherosclerosis. B cell receptors: …
Functional role of B cells in atherosclerosis
SD Ma, M Mussbacher, EV Galkina - Cells, 2021 - mdpi.com
… atherosclerosis-prone conditions. By summarizing current knowledge of B cells in and beyond
atherosclerosis… While OSE-derived antigens induce humoral response in atherosclerosis, …
atherosclerosis… While OSE-derived antigens induce humoral response in atherosclerosis, …
Adaptive response of T and B cells in atherosclerosis
DFJ Ketelhuth, GK Hansson - Circulation research, 2016 - Am Heart Assoc
… Particularly, humoral immunity to oxLDL has been proposed to play an important role in
CVD in several studies. It has been shown that plaque size correlates negatively with levels of …
CVD in several studies. It has been shown that plaque size correlates negatively with levels of …
Antibodies in action: the role of humoral immunity in the fight against atherosclerosis
JA Taylor, MA Hutchinson, PJ Gearhart, RW Maul - Immunity & Ageing, 2022 - Springer
… and further stimulate B cell antibody production. B cells in atherosclerosis meanwhile have
a mixed … The current model is that B-1 cells produce protective IgM antibodies in response to …
a mixed … The current model is that B-1 cells produce protective IgM antibodies in response to …
B cells in atherosclerosis: mechanisms and potential clinical applications
T Pattarabanjird, C Li, C McNamara - Basic to Translational Science, 2021 - jacc.org
… B cell–derived Igs modulate atherosclerosis, with a focus on the implications for potential
B-cell–targeted therapies for atherosclerotic … to induce a humoral response to limit the impact of …
B-cell–targeted therapies for atherosclerotic … to induce a humoral response to limit the impact of …
Beyond macrophages and T cells: B cells and immunoglobulins determine the fate of the atherosclerotic plaque
H Mangge, F Prüller, W Schnedl, W Renner… - International Journal of …, 2020 - mdpi.com
… fight against atherosclerotic endpoints. This review will reflect the putative role of B cells in
… We will also discuss the clinical therapeutic potency of B cell modulations on the process of …
… We will also discuss the clinical therapeutic potency of B cell modulations on the process of …
Follicular B cells promote atherosclerosis via T cell–mediated differentiation into plasma cells and secreting pathogenic immunoglobulin G
C Tay, YH Liu, P Kanellakis, A Kallies, Y Li… - Arteriosclerosis …, 2018 - Am Heart Assoc
… evidence that FO B cells promote development of atherosclerosis via … Mixed chimeric Ldlr
−/− mice whose B cells were deficient in … humoral immunity independently of naïve CD4 + T cell …
−/− mice whose B cells were deficient in … humoral immunity independently of naïve CD4 + T cell …
Gut microbiota and atherosclerosis: role of B cell for atherosclerosis focusing on the gut-immune-B2 cell axis
L Chen, T Ishigami, H Doi, K Arakawa… - Journal of Molecular …, 2020 - Springer
… Furthermore, a potential translational extension of the current research would be to better
characterize the specific humoral immunity in individuals with atherosclerosis. We sought to …
characterize the specific humoral immunity in individuals with atherosclerosis. We sought to …