Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling
M Yu, S Han, M Wang, L Han, Y Huang, P Bo, P Fang… - Phytomedicine, 2022 - Elsevier
Background Type 2 diabetes mellitus is a complex metabolic disorder associated with
obesity, glucose intolerance and insulin resistance. Activation of GALR2 has been proposed
as a therapeutic target for the treatment of insulin resistance. The previous studies showed
that baicalin could mitigate insulin resistance, but the detailed mechanism of baicalin on
insulin resistance has not been fully explored yet. Purpose In the present study, we
evaluated whether baicalin mitigated insulin resistance via activation of GALR2 signaling …
obesity, glucose intolerance and insulin resistance. Activation of GALR2 has been proposed
as a therapeutic target for the treatment of insulin resistance. The previous studies showed
that baicalin could mitigate insulin resistance, but the detailed mechanism of baicalin on
insulin resistance has not been fully explored yet. Purpose In the present study, we
evaluated whether baicalin mitigated insulin resistance via activation of GALR2 signaling …
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