Markov-modulated continuous-time Markov chains to identify site-and branch-specific evolutionary variation in BEAST

G Baele, MS Gill, P Bastide, P Lemey… - Systematic …, 2021 - academic.oup.com
… fit compared to the ones obtained in this section for the psaB and ndhD genes, as well as
the ability of state-of-the-art Bayesian model selection to select the generative substitution …

Markov-modulated continuous-time Markov chains to identify site-and branch-specific evolutionary variation

G Baele, MS Gill, P Lemey, MA Suchard - arXiv preprint arXiv:1906.05136, 2019 - arxiv.org
… These analyses of simulated data show that MMMs can easily be used in combination with
recent developments in Bayesian model selection, and provide additional support for our …

Bayesian analysis of continuous time Markov chains with applications to phylogenetics

T Zhao - 2018 - open.library.ubc.ca
… Linear Models (GLM) ideas to Bayesian rate matrix … Model for Continuous Time Markov
Chains (GLM-CTMC) structured prior construction. In the motivating example of protein evolution, …

[HTML][HTML] Smoothed model checking for uncertain continuous-time Markov chains

L Bortolussi, D Milios, G Sanguinetti - Information and Computation, 2016 - Elsevier
… countable state space S and evolving in continuous time [18]. A … The choice of MITL is justified
because time-bounded linear … use the binomial observation model in Bayes's theorem. In …

General continuous-time Markov model of sequence evolution via insertions/deletions: are alignment probabilities factorable?

K Ezawa - BMC bioinformatics, 2016 - Springer
… In this study, we examine a general continuous-time Markov model of the evolution of an
entire sequence via insertions, deletions and substitutions. This model could be regarded as an …

Bayesian analysis of continuous time Markov chains with application to phylogenetic modelling

T Zhao, Z Wang, A Cumberworth, J Gsponer… - 2016 - projecteuclid.org
… For example, in the protein evolution problem motivating the work in this paper, one could
tie … We select a specific set of features, described in Supplement 8, that match the degrees of …

A gentle introduction to probabilistic evolutionary models

T Pupko, I Mayrose - 2020 - hal.science
continuous time Markov models used to describe sequence … The above models consist of
continuous time Markov chains … The introduction of Bayesian integration techniques in TKF91 …

Probabilistic model checking for continuous-time Markov chains via sequential Bayesian inference

D Milios, G Sanguinetti, D Schnoerr - … 2018, Beijing, China, September 4-7 …, 2018 - Springer
… 3.1, the moment closure method results in a system of ODEs that describe the evolution of …
within the continuous-time differential equations approach of [33], which dictates the choice of …

General continuous-time Markov model of sequence evolution via insertions/deletions: local alignment probability computation

K Ezawa - BMC bioinformatics, 2016 - Springer
… probabilities of sequence alignments via evolutionary processes on an entire sequence. …
under a continuous-time Markov model, which describes the stochastic evolution of an entire …

Probabilistic model checking for continuous time markov chains via sequential bayesian inference

D Milios, G Sanguinetti, D Schnoerr - arXiv preprint arXiv:1711.01863, 2017 - arxiv.org
… in a system of ODEs that describe the evolution of the expected values and the covariances
… the continuous-time differential equations approach of [33], which dictates the choice of …