Impact of gastrointestinal lipolysis on oral lipid-based formulations and bioavailability of lipophilic drugs
F Carrière - Biochimie, 2016 - Elsevier
… of type III including an oil phase and surfactants are the basis for the so-called Self-Emulsifying …
drug absorption. Panel A: Fasted state study of Probucol oral bioavailability in minipigs. …
drug absorption. Panel A: Fasted state study of Probucol oral bioavailability in minipigs. …
Preparation and evaluation of probucol-phospholipid complex with enhanced bioavailability and no food effect
Y Qian, G Chen, J Wang, L Ren - AAPS PharmSciTech, 2018 - Springer
… formulation of PRO, which can increase its oral absorption … -particles (6), lipid and surfactant
based dispersions (7), and self-… Phospholipid is a kind of biofunctional surfactants which can …
based dispersions (7), and self-… Phospholipid is a kind of biofunctional surfactants which can …
Probucol self-emulsified drug delivery system: stability testing and bioavailability assessment in human volunteers
… and the impact of the particle size on the drug absorption differs … surfactant and lipid phase
in the formulation. Consequently, formulations with matching particle size, but different lipid …
in the formulation. Consequently, formulations with matching particle size, but different lipid …
Critical aspects involved in lipid dispersion and digestion: emphasis on in vitro models and factors influencing lipolysis of oral lipid based formulations
… lipid excipient, surfactants, and co-solvents), the droplet size of … (LBFs) in enhancing drug
bioavailability. Static models … , DG, and MG-based LBFs of probucol. The results demonstrated …
bioavailability. Static models … , DG, and MG-based LBFs of probucol. The results demonstrated …
[HTML][HTML] Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method
F Li, L Li, S Wang, Y Yang, J Li, D Liu, S Zhang… - Asian Journal of …, 2019 - Elsevier
… Crystalline state is one of the key factors that influence the dissolution behavior of water …
instead of the incorporation of stabilizers or surfactants in the formulation. It also should be noted …
instead of the incorporation of stabilizers or surfactants in the formulation. It also should be noted …
50 years of oral lipid-based formulations: provenance, progress and future perspectives
… Lipid based formulations (LBF) provide well proven opportunities to enhance the oral absorption
… LBF (surfactants and cosolvents), have been described to impact intestinal permeability…
… LBF (surfactants and cosolvents), have been described to impact intestinal permeability…
Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
… Lipid-based formulations (LBFs) is a formulation strategy for … the influence of LBF intestinal
digestion on drug absorption. … as efficient as a lipid-based drug formulation containing the pre-…
digestion on drug absorption. … as efficient as a lipid-based drug formulation containing the pre-…
Formulation Strategies and Optimization of Poorly Water-Soluble Drugs for Preclinical and Clinical Applications
M Lavan - 2018 - search.proquest.com
… may actually influence oral drug absorption and impact clinical findings. … Surfactant-based
formulations can be found in oral … surfactants and amphiphilic polymers are utilized in oral lipid-…
formulations can be found in oral … surfactants and amphiphilic polymers are utilized in oral lipid-…
Self-nanoemulsifying systems for oral bioavailability enhancement: Recent paradigms
… , as it tends to influence the emulsification property at low … Like other lipid-based formulations,
SNEDDS are also … challenges of high levels of surfactants in the SNEDDS formulations, the …
SNEDDS are also … challenges of high levels of surfactants in the SNEDDS formulations, the …
Recent approaches to investigate drug delivery systems through the lymphatic pathway using oral lipid-based formulations
SJ Jeong, WY Song, CW Park, DW Kim - Journal of Pharmaceutical …, 2024 - Springer
… absorption of medications is significantly influenced by the … IV lipid formulations are based
on water-soluble surfactants … of excipients for lipid-based formulations is influenced by several …
on water-soluble surfactants … of excipients for lipid-based formulations is influenced by several …