All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium

BM Radu, AMM Osculati, E Suku, A Banciu, G Tsenov… - Scientific reports, 2017 - nature.com
characterization in mouse brain endothelium is lacking. Here, we show that all muscarinic
acetylcholine receptors (M … M 5 in the human brain microcirculation 18, 32 , which makes a full …

Distribution of muscarinic acetylcholine receptors in the CNS

R Schliebs, S Roßner - CNS Neurotransmitters and …, 2020 - taylorfrancis.com
… clearly demonstrating striking regional changes in the appearance … the cardiac muscarinic
acetylcholine receptor, Biochemistry, 26, … structure from Drosophila to human brain and detect …

Muscarinic receptor subtype distribution in the central nervous system and relevance to aging and Alzheimer's disease

EP Lebois, C Thorn, JR Edgerton, M Popiolek, S Xi - Neuropharmacology, 2018 - Elsevier
Muscarinic acetylcholine receptors (mAChRs) are G … of neocortical neurons in human brain
tissue obtained during epilepsy … , suggesting the M 1 receptor may be altered in AD and provi…

Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer's disease

MG Sabbir, M Swanson, BC Albensi - Frontiers in Cell and …, 2023 - frontiersin.org
… TEM analysis revealed that Chrm1 loss led to mitochondrial ultrastructural defects and
alteration in the tinctorial properties of cortical neurons causing a significant increase in the …

Loss of cholinergic receptor muscarinic 1 (CHRM1) protein in the hippocampus and temporal cortex of a subset of individuals with Alzheimer's disease, Parkinson's …

MG Sabbir, RC Speth… - Journal of Alzheimer's …, 2022 - content.iospress.com
… , comparative analysis of diseased and unaffected human brain … It was proposed that structural
alterations in cholinergic … above-mentioned important biological question by analyzing the …

[HTML][HTML] Cholinergic receptor alterations in the cerebral cortex of spinal cord injured rat

R Chinthu, TR Anju, CS Paulose - Biochemistry and Biophysics Reports, 2017 - Elsevier
cholinergic firing in locomotion, we focussed the study in understanding the cholinergic
alterations in cerebral … key enzymes in cholinergic pathway - acetylcholine esterase and choline …

A review of the cholinergic system and therapeutic approaches to treat brain disorders

D Bertrand, TL Wallace - Behavioral Pharmacology of the Cholinergic …, 2020 - Springer
acetylcholine receptors (mAChRs), present in both the … the receptor and aim to regulate
the ensuing biological response. … , will be accompanied by modifications in the functional and …

Distribution and function of the muscarinic receptor subtypes in the cardiovascular system

HC Saternos, DA Almarghalani… - Physiological …, 2018 - journals.physiology.org
Muscarinic acetylcholine receptors belong to the G protein-… Like acetic acid, choline is
also vital for various biological … the cardiovascular alterations will be the focal point. AChM1R …

M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer's disease pathology

JH Yi, DJ Whitcomb, SJ Park… - Brain …, 2020 - academic.oup.com
… cortical brain slice model, we find that postsynaptic muscarinic acetylcholine receptor function
… for mAChR function and disease modification in moderate stages of Alzheimer’s disease. …

Cholinergic system and post-translational modifications: an insight on the role in Alzheimer's disease

T Ahmed, S Zahid, A Mahboob… - Current …, 2017 - ingentaconnect.com
Alterations of muscarinic acetylcholine receptor subtypes in diffuse lewy body disease: …
alteration of various cholinergic markers in cortical and subcortical regions of human brain in …