Bioinspired engineering of a multivalent aptamer‐functionalized nanointerface to enhance the capture and release of circulating tumor cells

Y Song, Y Shi, M Huang, W Wang… - Angewandte Chemie …, 2019 - Wiley Online Library
capture and release of SW480 cells from spiked blood samples, we collected all the released
cells and extracted the whole genomic DNA for … sample after capture/release process was …

Bioinspired nano-plate-coral platform enabled efficient detection of circulating tumor cells via the synergistic capture of multivalent aptamer and tumor cell membrane

L Jia, X Zhen, L Chen, Q Feng, W Yuan, Y Bu… - Journal of Colloid and …, 2023 - Elsevier
… targeting of tumor cell membranes and lateral fluidity, thus enhancing capture performance.
… that long multivalent aptamer DNA strands can be combined with tumor cell membrane to …

Bioinspired DNA nanointerface with anisotropic aptamers for accurate capture of circulating tumor cells

W Qin, L Chen, Z Wang, Q Li, C Fan, M Wu… - Advanced …, 2020 - Wiley Online Library
… of multivalent binding between DNA nanosynapse and cell … a bioinspired nanoplatform
for precise capture of heterogeneous CTCs. The topology-defined anisotropic aptamer (DNA

DNA framework-programmed cell capture via topology-engineered receptor–ligand interactions

M Li, H Ding, M Lin, F Yin, L Song, X Mao… - Journal of the …, 2019 - ACS Publications
… With the inability to promote multivalent binding, 0-simplex can … capture of CTCs. To
evaluate the effect of topologically engineered RLIs on cell capture, we compared the cell capture

Biomimetic recognition strategy for efficient capture and release of circulating tumor cells

J Zheng, D Li, J Jiao, C Duan, Y Gong, H Shi, Z Wang… - Microchimica Acta, 2021 - Springer
… viability, but also reduce a tedious release process and … for the capture and release of
various tumor cells and will inspire … 4 NPs can capture target cells through multivalent aptamers. …

Double rolling circle amplification generates physically cross-linked DNA network for stem cell fishing

C Yao, H Tang, W Wu, J Tang, W Guo… - Journal of the …, 2020 - ACS Publications
cellular state of the enveloped BMSCs in the DNA network. BMSCs were stained with red
fluorescent dye CM-DiI, and DNA … II; the morphologies of the DNA network and BMSCs were …

Bioinspired and biomimetic delivery platforms for cancer vaccines

J Liu, SS Liew, J Wang, K Pu - Advanced Materials, 2022 - Wiley Online Library
… [ 12 ] Till date, multiple cancer vaccine strategies have been proposed using Ags such as
whole tumor cells, DCs or Ags in the form of proteins, peptides, DNA or mRNA. [ 13 ] Different …

Mimicking the cell: bio-inspired functions of supramolecular assemblies

Y Tu, F Peng, A Adawy, Y Men… - Chemical …, 2016 - ACS Publications
bioinspired functions and applications such as compartmentalization, transport, drug release,
… Before deciding to dive straight into the bioinspired function, we have chosen to review the …

Bioinspired three-dimensional hierarchical micro/nano-structured microdevice for enhanced capture and effective release of circulating tumor cells

L Wang, S Huang, QY Li, LY Ma, C Zhang, F Liu… - Chemical Engineering …, 2022 - Elsevier
… before and after release observed under an inverted fluorescence microscope. Survival of
captured and released cells was calculated by the ratio of living cells to total cells, which were …

Fluidic multivalent membrane nanointerface enables synergetic enrichment of circulating tumor cells with high efficiency and viability

L Wu, H Ding, X Qu, X Shi, J Yang… - Journal of the …, 2020 - ACS Publications
… The present work provides a new clue for the bioinspired design of nanobiointerfaces in
the biomedical field by leveraging natural cellcell interactions with a natural biomaterial. …