Bioinspired engineering of a multivalent aptamer‐functionalized nanointerface to enhance the capture and release of circulating tumor cells
Y Song, Y Shi, M Huang, W Wang… - Angewandte Chemie …, 2019 - Wiley Online Library
… capture and release of SW480 cells from spiked blood samples, we collected all the released
cells and extracted the whole genomic DNA for … sample after capture/release process was …
cells and extracted the whole genomic DNA for … sample after capture/release process was …
Bioinspired nano-plate-coral platform enabled efficient detection of circulating tumor cells via the synergistic capture of multivalent aptamer and tumor cell membrane
… targeting of tumor cell membranes and lateral fluidity, thus enhancing capture performance.
… that long multivalent aptamer DNA strands can be combined with tumor cell membrane to …
… that long multivalent aptamer DNA strands can be combined with tumor cell membrane to …
Bioinspired DNA nanointerface with anisotropic aptamers for accurate capture of circulating tumor cells
W Qin, L Chen, Z Wang, Q Li, C Fan, M Wu… - Advanced …, 2020 - Wiley Online Library
… of multivalent binding between DNA nanosynapse and cell … a bioinspired nanoplatform
for precise capture of heterogeneous CTCs. The topology-defined anisotropic aptamer (DNA …
for precise capture of heterogeneous CTCs. The topology-defined anisotropic aptamer (DNA …
DNA framework-programmed cell capture via topology-engineered receptor–ligand interactions
… With the inability to promote multivalent binding, 0-simplex can … capture of CTCs. To
evaluate the effect of topologically engineered RLIs on cell capture, we compared the cell capture …
evaluate the effect of topologically engineered RLIs on cell capture, we compared the cell capture …
Biomimetic recognition strategy for efficient capture and release of circulating tumor cells
J Zheng, D Li, J Jiao, C Duan, Y Gong, H Shi, Z Wang… - Microchimica Acta, 2021 - Springer
… viability, but also reduce a tedious release process and … for the capture and release of
various tumor cells and will inspire … 4 NPs can capture target cells through multivalent aptamers. …
various tumor cells and will inspire … 4 NPs can capture target cells through multivalent aptamers. …
Double rolling circle amplification generates physically cross-linked DNA network for stem cell fishing
C Yao, H Tang, W Wu, J Tang, W Guo… - Journal of the …, 2020 - ACS Publications
… cellular state of the enveloped BMSCs in the DNA network. BMSCs were stained with red
fluorescent dye CM-DiI, and DNA … II; the morphologies of the DNA network and BMSCs were …
fluorescent dye CM-DiI, and DNA … II; the morphologies of the DNA network and BMSCs were …
Bioinspired and biomimetic delivery platforms for cancer vaccines
… [ 12 ] Till date, multiple cancer vaccine strategies have been proposed using Ags such as
whole tumor cells, DCs or Ags in the form of proteins, peptides, DNA or mRNA. [ 13 ] Different …
whole tumor cells, DCs or Ags in the form of proteins, peptides, DNA or mRNA. [ 13 ] Different …
Mimicking the cell: bio-inspired functions of supramolecular assemblies
… bioinspired functions and applications such as compartmentalization, transport, drug release,
… Before deciding to dive straight into the bioinspired function, we have chosen to review the …
… Before deciding to dive straight into the bioinspired function, we have chosen to review the …
Bioinspired three-dimensional hierarchical micro/nano-structured microdevice for enhanced capture and effective release of circulating tumor cells
L Wang, S Huang, QY Li, LY Ma, C Zhang, F Liu… - Chemical Engineering …, 2022 - Elsevier
… before and after release observed under an inverted fluorescence microscope. Survival of
captured and released cells was calculated by the ratio of living cells to total cells, which were …
captured and released cells was calculated by the ratio of living cells to total cells, which were …
Fluidic multivalent membrane nanointerface enables synergetic enrichment of circulating tumor cells with high efficiency and viability
… The present work provides a new clue for the bioinspired design of nanobiointerfaces in
the biomedical field by leveraging natural cell–cell interactions with a natural biomaterial. …
the biomedical field by leveraging natural cell–cell interactions with a natural biomaterial. …