… from transporter gene deficiency or functional inhibition in the liver, kidney, gastrointestinal
… -gp, which is driven by the seizure activity rather than the epileptic drug itself. (82) Similar up…

… biotin deficiency either they inhibit biotin transport across the intestinal mucosa or they
accelerate biotin … In fact, it is contraindicated in epilepsy treated with antiepileptic drugs, notably …

… to make biotin available from either dietary, intestinal bacterial … were poorly controlled with
anticonvulsant medication in 40 … might be caused by an inhibition of biotin reabsorption by the …

… the BBB permeability of the biotinylated dextran (3 kDa), the … moderately high resistance
human intestinal epithelial cell line… , and administration of the antibody inhibited tumor growth in …

… therapeutic drugs inhibit the intestinal thiamine transporter … the potential for ThTR-2 inhibition
for novel compounds, and 3… relevant inhibitors identified in our prescription drug library …

… 2 (hTHTR2) which absorbs thiamine and its isoforms from the intestine. Thiamine (…
Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: …

… and non-competitive inhibitors and by protein kinases' … via different transport mechanisms
through intestinal epithelial cells. … delivery systems and avidin-biotin technology allows for the …

… acid, is a metabolic fermentation product of some gut bacteria and is often used as an anti-…
Avidin protein in egg white binds; 1.44 mg biotin/kg purified diet, inhibiting biotin absorption […

… Commonly used antiepileptic drugs are typically ineffective … Biotin therapy is crucial in
the case of biotinidase deficiency … the use of carbonic anhydrase inhibitors was found to be …

… carrier transporters throughout the gastrointestinal tract represents numerous potential … sites
in the gastrointestinal tract. Additionally, exciting improvements in oral drug delivery systems …