… Drugs that inhibit BSEP function with IC50 values less than 25 μM [391] or decrease its
expression [199] can cause Drug-Induced Liver Injury (DILI) in the form of cholestatic liver injury. …

… inhibit absorption of thiamine by the primary intestinal … medications, several of which may
inhibit the transporter. … Although THTR- 2 is a thiamine transporter that does not transport biotin […

… of efficacy of ABC drug transporter inhibitors to increase the … We have reported that the
inhibition of intestinal ABCG2 in … )-b-poly(ethylene glycol)-biotin nanoparticulate system which can …

… Vitamin D deficiency in patients on chronic anticonvulsant drugs such … Vitamin K, biotin, and
small amounts of vitamin B12 are … drugs, can inhibit an intestinal enzyme necessary for drug …

… is a transporter for pantothenic acid (vitamin B5) and biotin (… Intestinal α-glucosidase inhibitors
affect the rate of digestion … by competitively and irreversibly inhibiting glucosidases in the …

… of anticonvulsant drugs. The antiepileptic effect of the medicine is caused by the inhibition
of … the probability of high to low intestinal absorption of a drug. The optimal range of BBB …

… resistance to conventional antiepileptic drug therapy are common to … by competitive inhibition
of lysine uptake in the gut and the … an impairment of the endogenous recycling of biotin [11]. …

… , and Rc in the intestinal microbiota. Previous studies show … -epileptic effect via enhancing
the GABA-mediated inhibition … in the secondary antibodies: the biotinylated-goat anti-mouse …

… intestinal absorption between chromium and other metals, like zinc and iron [260,261].
Another suspected mechanism is the inhibition of gastrointestinal prostaglandin synthesis [262]. …

… tumors in enterochromaffin cells in the gut. Cerebral 5HIAA can undergo efflux from the
brain by active transport and probenecid is a drug that can inhibit this transporter (Corcuff et al. …