Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
… activation in the bladder and bladder afferent pathways, could be a potential treatment that
… urothelium and smooth muscles, leading to stimulation of bladder afferents and induction of …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
bladder is initially areflexic but then becomes hyperreflexic … , inducing initially an areflexic
bladder leading to urinary … Aδ-fiber bladder afferent pathways to enhance the bladder-to-…

[HTML][HTML] Afferent pathway-mediated effect of α1 adrenergic antagonist, tamsulosin, on the neurogenic bladder after spinal cord injury

JH Han, SE Kim, IG Ko, J Kim… - International Neurourology …, 2017 - ncbi.nlm.nih.gov
… exact mechanism and effects of tamsulosin on the afferent … in bladder afferent pathways
and NGF-induced reduction in A-… , C-fiber afferent neurons mediate bladder hyperreflexia and …

Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management

KC Eldahan, AG Rabchevsky - Autonomic Neuroscience, 2018 - Elsevier
… Herein, we review the pathophysiological mechanisms germane … afferents entering the spinal
cord as well as glutamatergic … in the magnitude of AD induced by bladder distension during …

Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury

S Hou, DM Carson, D Wu, MC Klaw, JD Houlé… - Experimental …, 2016 - Elsevier
… the underlying mechanism behind bladder hyperreflexia in … injury-induced intraspinal
plasticity, as a high level of injury … To check for possible TH + efferents, the ventral efferent nerve

Reduction in bladder-related autonomic dysreflexia after onabotulinumtoxinA treatment in spinal cord injury

RJ Fougere, KD Currie, MK Nigro, L Stothers… - Journal of …, 2016 - liebertpub.com
… sitting the participant upright to induce orthostatic BP response, … of afferent sensory information
from the urinary bladder to the … of detrusor hyperreflexia in spinal cord injured patients: a …

Autonomic dysreflexia following spinal cord injury

V Balik, I Šulla - Asian Journal of Neurosurgery, 2022 - thieme-connect.com
… in blood pressure induced by afferent sensory stimulation owing to … , also known as autonomic
hyperreflexia, AD syndrome, or … by the distension of urinary bladder, genitourinary tract …

Epidemiology and pathophysiology of neurogenic bladder after spinal cord injury

R Hamid, MA Averbeck, H Chiang, A Garcia… - World journal of …, 2018 - Springer
… the bladder afferent neurons leading to neuropathic bladder … The primary mechanism involves
the initial mechanical injury … of NGF into the rat bladder induces bladder hyperactivity and …

Intraspinal plasticity associated with the development of autonomic dysreflexia after complete spinal cord injury

FM Michael, SP Patel, AG Rabchevsky - Frontiers in Cellular …, 2019 - frontiersin.org
… between injury-induced sprouting of pelvic visceral afferent C-… pathways disrupted/rerouted
by complete spinal cord injury (… Sensory afferent fibers (blue) from the distended bladder or …

… facilitation of the spinal locomotor central pattern generator and reflex circuits by somatosensory feedback from the lumbar and perineal regions after spinal cord injury

AN Merlet, J Harnie, A Frigon - Frontiers in Neuroscience, 2021 - frontiersin.org
… of urine in the bladder, as we thoroughly empty the bladders … brain that induces and maintains
plasticity in the spinal cord. … foot afferents, as well as the potential mechanisms involved. …