Body mass index and molecular subtypes of colorectal cancer

N Murphy, CC Newton, M Song… - … the National Cancer …, 2023 - academic.oup.com
… hypermethylation of promoter CpG island sites, causing … However, no evidence of
heterogeneity by CIMP status was … age, sex, education, smoking, physical activity, regular use of …

Global differences in the prevalence of the CpG island methylator phenotype of colorectal cancer

SM Advani, PS Advani, DW Brown, SM DeSantis… - BMC cancer, 2019 - Springer
CpG Island Methylator Phenotype (CIMP) is an epigenetic phenotype in CRC characterized
by hypermethylation of CpG islands in … geographical regions, no studies have compared …

Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort

KH Chen, LI Lin, CT Yuan, LH Tseng, YL Chao… - … Journal of Cancer, 2021 - nature.com
… CIMP-high CRC, a positive association between body mass index (BMI) (kg/… physical
activities, compared to CIMP-low/negative CRC. One meta-analysis also revealed that there was no

Physical activity and colorectal cancer prognosis according to tumor-infiltrating T cells

H Koh, T Hamada, M Song, L Liu, Y Cao… - JNCI Cancer …, 2018 - academic.oup.com
… We observed no differential survival association of physical activity by densities of CD8 + …
Using bisulfite-treated DNA, we quantified DNA methylation in eight CpG island methylator …

Epidemiology and molecular-pathologic characteristics of CpG Island methylator phenotype (CIMP) in colorectal cancer

SM Advani, MD Swartz, J Loree, JS Davis… - … colorectal cancer, 2021 - Elsevier
… an epigenetic phenotype in colorectal tumors characterized by significant hypermethylation
… Also, we found no differences in CIMP-H prevalence across methodologic subtypes, making …

Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular …

H Jayasekara, DR English, A Haydon… - … journal of cancer, 2018 - Wiley Online Library
CpG island methylator phenotype … Among eligible MCCS participants with no previous
diagnosis of cancer at enrolment, 1,227 incident CRC cases were diagnosed. We excluded 43 …

Risk factors and incidence of colorectal cancer according to major molecular subtypes

L Wang, X He, T Ugai, K Haruki, CH Lo… - JNCI cancer …, 2021 - academic.oup.com
… instability (MSI), CpG island methylator phenotype (CIMP), and … Physical activity is calculated
by the product sum of the … ), family history of colorectal cancer (yes or no), history of lower …

Association between physical activity and colorectal cancer risk and prognosis: A meta-analysis

XY Zhou, L Yan, LL Wang, J Wang - Cancer Treatment and Research …, 2016 - Elsevier
… Reverse correlation has been frequently reported between physical activity (PA) and
colorectal cancer (CRC) risk and mortality in numerous prospective studies. But the contradictive …

Lifestyle and dietary environmental factors in colorectal cancer susceptibility

N Murphy, V Moreno, DJ Hughes, L Vodicka… - Molecular aspects of …, 2019 - Elsevier
physical activity and greater height and body mass index (BMI) were primarily associated with
an increased risk of distal or proximal colon cancer, … lower risk for MSI-high tumors, with no

[HTML][HTML] Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: a multinational cohort study

N Murphy, HA Ward, M Jenab, JA Rothwell… - Clinical …, 2019 - Elsevier
… an increased risk of proximal colon and rectal cancer, whereas no … result we observed for
physical activity with rectal cancer. … , and CpG island methylator phenotype–positive tumors, are …