Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
… of manipulation and evasion strategies used by Cryptococcus… , calcium flux and protease
activity, rendering the phagosome … of Cryptococcus to proliferate inside macrophages and then …
activity, rendering the phagosome … of Cryptococcus to proliferate inside macrophages and then …
Dragotcytosis: elucidation of the mechanism for Cryptococcus neoformans macrophage-to-macrophage transfer
Q Dragotakes, MS Fu, A Casadevall - The Journal of Immunology, 2019 - journals.aai.org
… of yeast cells in some phagosomes, particularly larger ones … in macrophages where the
fungal cell cannot escape, the … and manipulation of the phagosome by a fungal pathogen. …
fungal cell cannot escape, the … and manipulation of the phagosome by a fungal pathogen. …
Lipids affect the Cryptococcus neoformans-macrophage interaction and promote nonlytic exocytosis
SJ Nolan, MS Fu, I Coppens… - Infection and …, 2017 - Am Soc Microbiol
… during the interaction of Cryptococcus neoformans with macrophages in … As the phagosomes
of macrophages have limited glucose … An initial event in the escape of C. neoformans from …
of macrophages have limited glucose … An initial event in the escape of C. neoformans from …
Formation and maturation of the phagosome: a key mechanism in innate immunity against intracellular bacterial infection
… Phagosomes then interact with lysosomes to form … on phagosome maturation among the
various immune evasion … phagocytes, including macrophages, neutrophils and dendritic cells. …
various immune evasion … phagocytes, including macrophages, neutrophils and dendritic cells. …
The outcome of the Cryptococcus neoformans–macrophage interaction depends on phagolysosomal membrane integrity
…, MS Fu, Q Dragotakes, C Coelho… - The Journal of …, 2018 - journals.aai.org
… by macrophages it resides within a mature phagosome, where it … neoformans escape from
macrophages during this time course … Chemical manipulation of PMP affects the outcome of C. …
macrophages during this time course … Chemical manipulation of PMP affects the outcome of C. …
Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way
EJ Santiago-Burgos, PV Stuckey… - Frontiers in Cellular …, 2022 - frontiersin.org
… interactions driving disease establishment is Cryptococcus’s … or Mycobacteria, escape from
the phagosome before it acidifies; … albicans’s phagosomes acidify faster in M1 macrophages …
the phagosome before it acidifies; … albicans’s phagosomes acidify faster in M1 macrophages …
Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
… neoformans may manipulate phagosome maturation to enhance its own … by macrophages
are degraded in the phagosome, C. neoformans uses at least three mechanisms to escape …
are degraded in the phagosome, C. neoformans uses at least three mechanisms to escape …
Cholesterol and sphingomyelin are critical for Fcγ receptor–mediated phagocytosis of Cryptococcus neoformans by macrophages
… macrophages play a key role in the outcome of a cryptococcal infection, it is crucial to understand
factors that mediate phagocytosis of C… govern macrophages' ability to phagocytose C. …
factors that mediate phagocytosis of C… govern macrophages' ability to phagocytose C. …
Control of phagocytosis by microbial pathogens
E Uribe-Querol, C Rosales - Frontiers in immunology, 2017 - frontiersin.org
… , and even physical escape from the phagosome. Our … This last step is enhanced through
interactions with GTPase-… by macrophages by preventing fusion between phagosomes and …
interactions with GTPase-… by macrophages by preventing fusion between phagosomes and …
[HTML][HTML] Characterizing the mechanisms of nonopsonic uptake of cryptococci by macrophages
… evade clearance by the host immune system by hiding and persisting within macrophages
(2… this interaction for Cryptococci remains unknown. In this article, we show that nonopsonized …
(2… this interaction for Cryptococci remains unknown. In this article, we show that nonopsonized …