… Afterward, lead compounds are tested in vivo to identify drug … mimic the function of C3
exoenzyme residues Asn98, Val96 and … the electronic effects of the substituents had little impact …

… Accordingly, lack of Smad3 has been associated to reduced secretion of ECM … in vivo
PVR mouse model [133]. Interestingly, the upstream blockade of RhoA by C3 exoenzyme or …

… -ribosylating toxin, and an C3 exoenzyme which has led to BoNT… For some years, an in vitro
replacement for the mouse … structurally similar to the toxin but lacking the zinc-binding motif …

… not affect SMNs isolated from task1 −/− embryos (SMNs task1−/− ), it lowered IME and increased
TASK-dependent changes in SMNs wt and SMNs task3−/− (lacking … estimated in vitro by …

… in the brain, was lacking because the specific antibody for this … between Rhotekin and PIST
by in vitro pull-down assays and … of Rho by C3 exoenzyme had little effect on the interaction. …

… , we generated a PRG2 deletion mutant lacking the poly-E-box … We also tested the effect of
induction of Prg2 expression in … in axon morphogenesis and branching, we performed in vitro …

… responses, the lack of functional improvement associated with … The downregulation of
Vcam1 and Cdh15 in SRCs C3 … terms of regenerative capacity in mice; however, their effect on …

… spectrum of eye abnormalities including lack of iris, cataract, … In vitro studies also confirmed
that the normal expression of … -specific expression of C3-exoenzyme not only show defects in …

… 304308 RhoA inhibition using C3 exoenzyme and … 365 But what is lacking is the
understanding of the effects of … promotes axon regeneration in the rat optic nerve in vivo and …

… ROCK signal has harmful effects on several in vivo models of I… botulinum C3-transferase
under the control of T cell-specific … diabetic nephropathy but has no effects on blood pressure […