[PDF][PDF] RESPONSES OF AUDITORY SUPPORTING CELLS TO HAIR CELL DAMAGE AND DEATH
T Anttonen - helda.helsinki.fi
… lack vital information on how to therapeutically target supporting cells and whether this can
be achieved in a safe way that permits hair cell protection or regeneration… in vivo functions are …
be achieved in a safe way that permits hair cell protection or regeneration… in vivo functions are …
Development of 3-Dimensional skin infection models for the evaluation of antimicrobial strategies
GAY Beleid - 2019 - shura.shu.ac.uk
… Development of In vitro skin models to investigate the effect … This is currently hampered by
the lack of in vitro models of … infected wounds, together with effects they exert on mammalian …
the lack of in vitro models of … infected wounds, together with effects they exert on mammalian …
Forkhead domain inhibitory-6 attenuates subconjunctival fibrosis in rabbit model with trabeculectomy
C Lan, J Tan, L Tang, G Liu, L Huang, X Luo… - Experimental Eye …, 2021 - Elsevier
… -6 exerts an inhibitory effect on subconjunctival fibrosis caused … matrix and, consequently,
lack of filtering space for aqueous … In the current study, in vivo confocal microscopic analysis …
lack of filtering space for aqueous … In the current study, in vivo confocal microscopic analysis …
[PDF][PDF] Microglia dysfunction caused by the loss of rhoa disrupts neuronal physiology and leads to neurodegeneration
R Socodato, CC Portugal, T Canedo, A Rodrigues… - Cell Reports, 2020 - cell.com
… We then evaluated the impact of microglia-dependent neuro… Because blocking Src activity
in microglia lacking Rhoa abro… to TNF, our in vitro data demonstrated that TNF signaling was …
in microglia lacking Rhoa abro… to TNF, our in vitro data demonstrated that TNF signaling was …
Lysophospholipid mediators in health and disease
… effect of LPA on various cell types in vitro. For example, LPA promotes cell proliferation (78)
and can retract elongating axons … Furthermore, lack of a labile lipid ester linkage makes S1P …
and can retract elongating axons … Furthermore, lack of a labile lipid ester linkage makes S1P …
Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans
K Modzelewska, L Brown, J Culotti… - Development, 2020 - journals.biologists.com
… did not affect the 3 fate frequency of P4.p, and effects on P3.p … C3 exoenzyme from Clostridium
botulinum, which specifically ADP ribosylates and inactivates RhoA, B and C, and has no …
botulinum, which specifically ADP ribosylates and inactivates RhoA, B and C, and has no …
[HTML][HTML] Some Examples of Bacterial Toxins as Tools
G Schmidt - Toxins, 2024 - mdpi.com
… inactivation and Rho-independent effects by the toxin induce … C3 lacks a binding and
translocation domain and therefore … depleting PD1-expressing cells in vitro and in mice [49]. An …
translocation domain and therefore … depleting PD1-expressing cells in vitro and in mice [49]. An …
Adhesion G protein–coupled receptors as drug targets
RH Purcell, RA Hall - Annual review of pharmacology and …, 2018 - annualreviews.org
… RGS domain of p115RhoGEF, C3 exoenzyme, and dominant … sprouting in vitro and inhibits
tumor growth in vivo, indicating … disease characterized by a lack of normal joint flexibility and …
tumor growth in vivo, indicating … disease characterized by a lack of normal joint flexibility and …
Improving chemotherapeutic regimens by mitigating hearing loss as a limiting side-effect and examining transition metal ions as a ligand for zebrafish Tlr4
A Fox - 2023 - era.library.ualberta.ca
… vivo. By creating a heterologous cell system using zebrafish Tlr4, we extended these findings
… Bhavsar lab was responsible for the in vitro cell culture work. Christie Li generated gRNA …
… Bhavsar lab was responsible for the in vitro cell culture work. Christie Li generated gRNA …
[PDF][PDF] Ocular Gene Therapy
M Naser, MM Nasr, LH Shehata - 2022 - researchgate.net
… surface have been offered in vitro or the utilization of animal … are its biodegradability and
lack of toxicity. Another NP … -mediated switch of exoenzyme C3 transferase gene, which …
lack of toxicity. Another NP … -mediated switch of exoenzyme C3 transferase gene, which …