Differences in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferative glomerulonephritis

Y Kawasaki, S Kanno, A Ono, Y Suzuki, S Ohara… - Pediatric …, 2016 - Springer
complement component C3 glomerulonephritis (C3GN), we retrospectively evaluated differences
in the clinicopathological findings … exclusive deposition of C3 at the glomerular level, as …

[HTML][HTML] Complement dysregulation in glomerulonephritis

K Kaartinen, A Safa, S Kotha, G Ratti, S Meri - Seminars in immunology, 2019 - Elsevier
… careful examination of the complement abnormality. Differential … complement attack influences
the function of the glomeruli. … disease (DDD) and C3 glomerulonephritis (C3GN) based on …

C3 Glomerulopathy

M Riedl, P Thorner, C Licht - Pediatric Nephrology, 2017 - Springer
glomerulonephritis has resulted in its re-classification as complement C3 glomerulopathy
(C3G) … a–c Typical membranoproliferative GN results in a cellular glomerulus with expanded …

[HTML][HTML] C3 glomerulopathy: a review with emphasis on ultrastructural features

J Hou, KYM Ren, M Haas - Glomerular Diseases, 2022 - karger.com
… Patients tested for complement abnormalities can have a variety of complement factor genetic
… acute PIGN from C3G in those difficult cases with overlapping clinicopathologic features. …

C3 glomerulopathy: ten years' experience at Mayo Clinic

A Ravindran, FC Fervenza, RJH Smith… - Mayo Clinic …, 2018 - Elsevier
findings, triggering factors, complement abnormalities, … the common denominator of
glomerular C3 accumulation, our … clinicopathological findings, triggering events, complement

C3 glomerulopathy—understanding a rare complement-driven renal disease

RJH Smith, GB Appel, AM Blom, HT Cook… - Nature reviews …, 2019 - nature.com
… In PIGN, complement abnormalities are transient and C3 … as C3 glomerulopathy is warranted
if C3 levels remain … to human C3 glomerulopathy, including C3 glomerular deposition in the …

Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of the
alternative complement pathway in plasma and the glomerularabnormalities in complement

C3 glomerulopathy: pathogenesis and treatment

SB Ahmad, AS Bomback - Advances in Chronic Kidney Disease, 2020 - Elsevier
glomerulus, control of the complement pathway is important in maintaining neutrality. Glycocalyx
is a major component of the glomerular … to screen for complement abnormality is CH50, …

Autoimmune abnormalities of the alternative complement pathway in membranoproliferative glomerulonephritis and C3 glomerulopathy

M Noris, R Donadelli, G Remuzzi - Pediatric Nephrology, 2019 - Springer
glomerular complement deposits as well as in glomerular lesions in DDD. At variance with
findings in C3GN and DDD, terminal complement … in IC-MPGN glomerular deposits [60] which …

[HTML][HTML] C3 glomerulopathy and related disorders in children: etiology-phenotype correlation and outcomes

EKS Wong, KJ Marchbank… - Clinical Journal of the …, 2021 - journals.lww.com
… Membranoproliferative GN (MPGN) is a pattern of glomerular injury … C3 glomerulopathy
on the basis of relative complement and Ig staining on biopsy specimens. C3 glomerulopathy