… activated CD8 + T cells from tissues (36), we induced disease by transferring CD4 + T cells
… observed when 8.8 CD8 + T cells infiltrate the brain influenced the inflammatory infiltrate, we …

… Although cytotoxic CD8 T cells exhibit gliotoxic and neurotoxic properties … inflammatory
demyelination, alternative CD8 T cell subsets have been identified that possess anti-inflammatory …

… T cells into the CNS (16). Our findings showed that MRI allowed the detection of inflammatory
demyelination independently of T cell … lesion stratification by informing on T cell load, thus …

… T cells were considered as documented players in participating the progress of inflammatory
demyelinating disease … naïve CD8 + T cells and decreased effector/memory CD8 + T cells …

… Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS), leading to irreversible neuronal damage and, as a consequence, clinical disability…

… that cytotoxic T cells may in part selectively mediate the inflammatory … CD8 + cells (Durrenberger
et al., 2012). Interestingly, lower numbers of circulating regulatory T cells (FoxP3 +, CD8 …

… from a predominantly CD4 + T cell field to include CD8 + cytotoxic T cells as a novel effector
… is a monophasic inflammatory demyelinating disease predominantly affecting children. It …

… Multiple sclerosis is an inflammatory demyelinating disease in which active demyelination
… In this study, we performed an in-depth phenotypic characterization of T and B cell infiltrates …

… CD8 T cells in vivo, we show that LM infection induced disease suppressive CD8 T cells
that protected and treated PLP 178-191 disease. Importantly, a combination of PLP 178-191 -…

… inflammatory demyelinating mouse model. Here we report that OPC differentiation is inhibited
by both effector T cells … antigen to cytotoxic CD8 T cells, resulting in OPC death. In human …