CSF inflammatory biomarkers responsive to treatment in progressive multiple sclerosis capture residual inflammation associated with axonal damage

J Romme Christensen, M Komori… - Multiple Sclerosis …, 2019 - journals.sagepub.com
… treatment increased CSF sCD163, … CSF studies and histopathology studies in progressive
MS. During treatment, we also observed correlation between CSF biomarkers of inflammation

[HTML][HTML] Mechanisms of neurodegeneration and axonal dysfunction in progressive multiple sclerosis

J Correale, M Marrodan, MC Ysrraelit - Biomedicines, 2019 - mdpi.com
Axonal damage in white-matter lesions correlates with the … levels of inflammatory cytokines
such as IFN-γ, and GM-CSF, … cause axonal damage release NF proteins into the CSF and …

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

R Magliozzi, OW Howell, R Nicholas… - Annals of …, 2018 - Wiley Online Library
… with limited repair, axonal loss, diffuse inflammatory changes in the … and CSF derived from
27 postmortem secondary progressive … and cerebrospinal fluid (CSF) of multiple sclerosis and …

[HTML][HTML] Intrathecal inflammation in progressive multiple sclerosis

S Monaco, R Nicholas, R Reynolds… - International journal of …, 2020 - mdpi.com
… CP, and their correlation with damage to neighboring nervous … intrathecal inflammation
compartmentalized in the CSF and … inflammation, white and grey demyelination, and axon loss in …

Defining active progressive multiple sclerosis

F Sellebjerg, L Börnsen, C Ammitzbøll… - Multiple Sclerosis …, 2017 - journals.sagepub.com
CSF biomarkers that were increased in progressive MS patients by Spearman’s rank correlation
… the relationship between inflammation, demyelination and neuronal/axonal damage in …

The CSF profile linked to cortical damage predicts multiple sclerosis activity

R Magliozzi, A Scalfari, AI Pisani, S Ziccardi… - Annals of …, 2020 - Wiley Online Library
… with axonal loss and diffuse inflammatory changes in the … in the CSF from 27 postmortem
secondary progressive MS … that the characterization of CSF inflammatory profile allows to …

[HTML][HTML] Relationship between cerebrospinal fluid biomarkers of inflammation and tissue damage in primary progressive multiple sclerosis

J Talbot, HH Chow, M Mahler, S Buhelt… - Multiple sclerosis and …, 2022 - Elsevier
correlations between CSF cytokines and found that several cytokines were closely and
significantly correlated … of inflammation found to have increased concentrations in CSF in our …

[PDF][PDF] Inflammatory mechanisms underlying cortical injury in progressive multiple sclerosis

LR Zuroff, JA Benjamins, A Bar-Or, RP Lisak - Neuroimmunol …, 2021 - f.oaes.cc
… and correlation with cognitive impairment in multiple sclerosis. … bands in multiple sclerosis
patients: a combined CSF and MRI … with diffuse axonal loss in multiple sclerosis spinal cords. …

[HTML][HTML] CSF neurofilament light chain levels in primary progressive MS: signs of axonal neurodegeneration

M Pawlitzki, S Schreiber, D Bittner, J Kreipe… - Frontiers in …, 2018 - frontiersin.org
axonal injury after acute inflammatory events in patients with multiple sclerosis (MS), and
rapidly progressive … rapid neurodegenerative (ALS) processes, but do not correlate with …

[HTML][HTML] Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study

G Farina, R Magliozzi, M Pitteri, R Reynolds… - Journal of …, 2017 - Springer
… Pearson correlation analysis between the CSF levels of … higher degree of neuronal and
axonal damage in this subgroup of … CSF obtained from secondary progressive multiple sclerosis (…