[HTML][HTML] Duality of B cell-CXCL13 axis in tumor immunology

AJ Rubio, T Porter, X Zhong - Frontiers in Immunology, 2020 - frontiersin.org
… helper T cells and is essential for naive B cell homing and organization … immunity to the
peritoneal cavity (70). This is evidenced in CXCL13-deficient mice which have reduced B1 B cell

[HTML][HTML] CXCL13 in cancer and other diseases: biological functions, clinical significance, and therapeutic opportunities

SH Gao, SZ Liu, GZ Wang, GB Zhou - Life, 2021 - mdpi.com
cells in SLOs are B-2 cells, CXCL13 also recruits B-1 cells into the body cavity, which triggers
early immune … B cells homing into the TME via the CXCL13/CXCR5 axis include pro-tumor …

[HTML][HTML] Role of the CXCL13/CXCR5 axis in autoimmune diseases

Z Pan, T Zhu, Y Liu, N Zhang - Frontiers in Immunology, 2022 - frontiersin.org
… In addition, CXCL13 and CXCR5 are required for B-cell homing in … through attracting B1 cell
toward the body cavity. In … Anti-CXCL13 antibody reduced B cells in the lymphoid infiltration, …

CXCL13/CXCR5 signaling axis in cancer

M Hussain, D Adah, M Tariq, Y Lu, J Zhang, J Liu - Life sciences, 2019 - Elsevier
… IgM antibodies for early protection from infections [41,48]. CXCL13/CXCR5-derived B-1 B
cells homing to body cavities is thus … of an early B cell-mediated innate immune response [41]. …

CXCL13 signaling in the tumor microenvironment

M Hussain, J Liu, GZ Wang, GB Zhou - … : The Role of Chemokines–Part B, 2021 - Springer
… by regulating noncancerous cells, particularly the immune cells, … For instance, CXCL13-CXCR5-derived
homing of B-1 B cells… [41]—to body cavities plays a dominant role in balanced …

[HTML][HTML] PD-1+ CXCR5− CD4+ Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma

JP Li, CY Wu, MY Chen, SX Liu, SM Yan… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
… Induction of Th-CXCL13 cells links innate inflammation to immune privilege in tumor-associated …
We added an IL-2-neutralizing antibody into the differentiation mixtures in vitro, which …

[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer

B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
… (CXCL13), originally identified as a B-cell chemokine, plays an important role in the immune
… chemotaxis of nearby responding cells, including the homing and positioning of mature T …

[PDF][PDF] IL-4Rα-expressing B cells are required for CXCL13 production by fibroblastic reticular cells

LK Dubey, B Ludewig, SA Luther, NL Harris - Cell reports, 2019 - cell.com
… fibroblasts in the development of CXCL13+ MRC-like cells and adaptive type 2 immunity in
… the germinal centers and to facilitate antibody production. FDC ablation disrupts proper B …

[HTML][HTML] A novel role for C5a in B-1 cell homeostasis

K Bröker, J Figge, AF Magnusen, RA Manz… - … in Immunology, 2018 - frontiersin.org
B-1 cell homing to body cavities is strongly dependent on … from B-1 cells, we hypothesized
that CXCL13 production from … in B-1 cell numbers is associated with increased nIgM antibody

[HTML][HTML] Regulated production of CXCL13 within the central nervous system

DN Irani - Journal of clinical & cellular immunology, 2016 - ncbi.nlm.nih.gov
… B cell numbers are slightly elevated, B cell homing to the peritoneal cavity is reduced in
these hosts [1,13]. When normal adult mice are given neutralizing anti-CXCL13 antibodies and …