[HTML][HTML] BRCA1-and BRCA2-associated hereditary breast and ovarian cancer

N Petrucelli, MB Daly, T Pal - 2022 - europepmc.org
… Molecular testing approaches can include a BRCA1 and BRCA2 gene panel and use of a
multigene … Pre-test prediction models of BRCA1 or BRCA2 mutation in breast/ovarian families …

Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

…, H Olsson, BRCA1 and BRCA2 Cohort Consortium - Jama, 2017 - jamanetwork.com
… differences in breast and ovarian cancer by mutation position (based on base-pair location)
using Cox regression. Mutations were … or BRCA2 gene. Consistent with those findings, …

[HTML][HTML] BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population

FC Cardoso, S Goncalves, PG Mele, NC Liria… - Human genomics, 2018 - Springer
BRCA1/2 mutation status in 398 EOC patients with two main goals: the benefits of detecting
hereditary breast/ovarian cancer … showed most mutations to be found in the BRCA1 gene, …

[HTML][HTML] Ovarian cancer in BRCA1 and BRCA2 gene mutation carriers: analysis of prognostic factors and survival

N Biglia, P Sgandurra, VE Bounous… - …, 2016 - ncbi.nlm.nih.gov
ovarian cancer treated between 2000 and 2009 who tested positive for BRCA1/2 mutation
(BRCA… patients with no family history of breast/ovarian cancer (controls) were enrolled. Clinical…

Ovarian cancer predisposition beyond BRCA1 and BRCA2 genes

A Pietragalla, M Arcieri, C Marchetti… - … of Gynecologic Cancer, 2020 - ijgc.bmj.com
mutations in BRCA1 or BRCA2 are associated with an increased lifetime risk of developing
breast and ovarian cancer, as well as pancreatic cancer… serous-like uterine cancer. There are …

[HTML][HTML] Differences in Ovarian and Other Cancers Risks by Population and BRCA Mutation Location

M Sekine, K Nishino, T Enomoto - Genes, 2021 - mdpi.com
… of ovarian cancer risk and BRCA mutation location, and differences of other BRCA-related
cancer risks by BRCA1/2 mutation… of the BRCA1 or BRCA2 gene for ovarian cancer has been …

[HTML][HTML] An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

E Przybytkowski, T Davis, A Hosny, J Eismann… - BMC cancer, 2020 - Springer
… We found that BRCA1/2 germline related breast and ovarian cancers … a range of phenotypes
similar to sporadic cancers. All … Thus, BRCA 1/2 germline mutation related hereditary breast

BRCA1 and BRCA2 mutations in ovarian cancer patients from China: ethnic‐related mutations in BRCA1 associated with an increased risk of ovarian cancer

T Shi, P Wang, C Xie, S Yin, D Shi… - … Journal of Cancer, 2017 - Wiley Online Library
… of BRCA1/2 mutations among Chinese ovarian cancer patients… 916 unselected consecutive
epithelial ovarian cancer (EOC) … In our series, although mutations in the BRCA1 gene spread …

[HTML][HTML] Identifying sequence variants contributing to hereditary breast and ovarian cancer in BRCA1 and BRCA2 negative breast and ovarian cancer patients

E Jarhelle, HMF Riise Stensland, GÅM Hansen… - Scientific reports, 2019 - nature.com
… leading cause of hereditary breast and ovarian cancer (HBOC). Together, mutated BRCA1
and BRCA2 are responsible for about 15–25% of familial breast and ovarian cancer cases 5,…

[HTML][HTML] Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers

RL Milne, AC Antoniou - Endocrine-related cancer, 2016 - erc.bioscientifica.com
associated with breast and ovarian cancer for mutation carriers: (i) GWAS for breast and ovarian
cancer … This paper forms part of a thematic review section on 20 Years of BRCA 1 and 2. …