Referred somatic hyperalgesia mediates cardiac regulation by the activation of sympathetic nerves in a rat model of myocardial ischemia

X Cui, G Sun, H Cao, Q Liu, K Liu, S Wang, B Zhu… - Neuroscience …, 2022 - Springer
… The cardiac innervation consists of the sympathetic and parasympathetic (vagus) nervous …
from the referred hyperalgesic areas with nociceptive stimulation on the forelimb or attenuated …

[HTML][HTML] Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia

S Salavatian, JD Hoang, N Yamaguchi… - JCI insight, 2022 - ncbi.nlm.nih.gov
… In this study, assessment of efferent vagal tone using direct vagal efferent nerve
recordings was not performed, and given the short duration (1 minute) of interventions, …

Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach

YE Kazci, SS Goktas, MS Aydin, B Karadogan… - Autonomic …, 2022 - Elsevier
… -Cre transgenic mice, we effectively visualized the vagal nodose afferent neural remodeling
… on neuropeptidergic and nociceptive subtypes (eg TRP channels) of NG afferents might …

Nociceptive pulmonary‐cardiac reflexes are altered in the spontaneously hypertensive rat

JS Hooper, KR Stanford, PA Alencar… - The Journal of …, 2019 - Wiley Online Library
… aberrant nociceptive pulmonary-cardiac reflexes in the SH rats … of the vagal efferent control
of the heart. Anaesthetized … that vagal fibres innervating the left side of the heart may also …

[HTML][HTML] Neuroanatomy, autonomic nervous system visceral afferent fibers and pain

T Sanvictores, P Tadi - 2020 - europepmc.org
Nociceptors detect pain and are innervated by type III and IV C fibers.[8] Chemoreceptors
detect … Cardiac vagal fibers innervate the aortic arch baroreceptors. Vagal GVA fibers innervate

Thoracic spinal cord and cervical vagosympathetic neuromodulation obtund nodose sensory transduction of myocardial ischemia

S Salavatian, E Beaumont, D Gibbons, M Hammer… - Autonomic …, 2017 - Elsevier
… differentially obtund nociceptive-related nodose afferent neuronal … This is in contradistinction
to the potential for vagal afferents to … therapies were done with intact innervation. Since …

[HTML][HTML] Cardiac vagal afferent neurotransmission in health and disease: review and knowledge gaps

VYH van Weperen, M Vaseghi - Frontiers in Neuroscience, 2023 - frontiersin.org
… , which mainly contains vagal afferent neurons innervating the … In rats with chronic heart
failure, decreased baroreceptor … Since after myocardial infarction, cardiac vagal nociceptive

Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure

RJ Adam, Z Xia, K Pravoverov, J Hong… - … Physiology-Heart …, 2019 - journals.physiology.org
… provide sensory afferent innervation for both the heart and lung. We … of cardiac nociception
to the central nervous system during … the potential contribution of vagal afferents and potential …

Activation of nociception‐sensitive ionotropic glutamate receptor‐expressing rostroventrolateral medulla neurons by stimulation of cardiac afferents in rats

MR Zahner, CC Oculam, E Beaumont - FASEB BioAdvances - Wiley Online Library
… not an intrinsic cardiac response to bradykinin or vagally mediated because these rats were
… to what we observed after stimulation of cardiac nociceptors with bradykinin.There is good …

Localization of TRPV1 and P2X3 in unmyelinated and myelinated vagal afferents in the rat

SM Hermes, MC Andresen, SA Aicher - Journal of chemical neuroanatomy, 2016 - Elsevier
… to identify distinct populations of vagal afferents to determine if key channels are selectively
localized to specific groups of afferent fibers. Vagal afferents were labeled with isolectin B4 (…