Promising gene delivery system based on polyethylenimine-modified silica nanoparticles

M Babaei, H Eshghi, K Abnous, M Rahimizadeh… - Cancer Gene …, 2017 - nature.com
carriers for assembly of such gene transfer system, the potential of modified silica nanoparticles
as a transfection … method to prepare cationic silica nanoparticles for gene delivery. For …

[HTML][HTML] Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery

A Slita, A Egorova, E Casals, A Kiselev… - Asian journal of …, 2018 - Elsevier
… with cationic polymers can provide safety of the fragile NA cargo and higher transfection
Thus, we can conclude that modified mesoporous silica nanoparticles can be considered as …

[HTML][HTML] Silica-based gene delivery systems: From design to therapeutic applications

AM Carvalho, RA Cordeiro, H Faneca - Pharmaceutics, 2020 - mdpi.com
… or drug delivery, having silica nanoparticles appeared in some clinical trials in the … silica
NPs were able to enhance gene delivery in cultured cells by helping other cationic transfection

Size-dependent gene delivery of amine-modified silica nanoparticles

M Yu, Y Niu, J Zhang, H Zhang, Y Yang, E Taran… - Nano Research, 2016 - Springer
… size of silica nanoparticles on gene transfection efficiency has … size of cationic silica
nanocarriers on gene delivery efficiency. … synthetic gene delivery systems with improved efficiency …

Novel luminescent silica nanoparticles (LSN): p53 gene delivery system in breast cancer in vitro and in vivo

C Rejeeth, A Salem - Journal of Pharmacy and Pharmacology, 2016 - academic.oup.com
… Taken together, our results reveal that cationic LSN-mediated p53 gene delivery may have
… In conclusion our results indicate that new cationic LSNs show higher transfection efficiency …

Enhanced gene delivery by polyethyleneimine coated mesoporous silica nanoparticles

H Zarei, R Kazemi Oskuee… - Pharmaceutical …, 2019 - Taylor & Francis
… The transfection results illustrated that the transfectionTransfection activity was decreased
with increase in cationic … the cationic polymer ratio and therefore transfection efficiency will be …

Co‐condensation synthesis of well‐defined mesoporous silica nanoparticles: effect of surface chemical modification on plasmid DNA condensation and transfection

M Mahmoodi, A Behzad‐Behbahani… - IET …, 2017 - Wiley Online Library
… Since making a balance between cationic density of nanoparticles and their charge density
causes better cellular interaction and endocytosis [60, 61], in the present study, N /P ratio as …

Biodegradable nano-organosilica gene carrier for high-efficiency gene transfection

K Zeng, L Ma, W Yang, S Lei, M Wang, Y You… - Journal of materials …, 2020 - pubs.rsc.org
… on the surface of silica nanoparticles, the polymer-modified silica nanoparticles can bind with
… the most commonly used cationic materials for the modification of gene carriers. But both of …

Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection

W Wu, A Ngo, W Ban, Y Zhong, D Cheng… - Journal of Materials …, 2022 - pubs.rsc.org
… (MSNs) have been widely employed as biocompatible gene … high gene transfection
performance, silica nanoparticle with … molecules onto silica nanoparticles, the cationic polymer of …

[HTML][HTML] Improved gene transfer with functionalized hollow mesoporous silica nanoparticles of reduced cytotoxicity

Z Zhan, X Zhang, J Huang, Y Huang, Z Huang, X Pan… - Materials, 2017 - mdpi.com
… their better gene delivery efficiency, inorganic porous nanoparticles combined with cationic
… To promote gene binding affinity and transfection efficiency, positively charged 1.8 kD PEI …