… These types of … neuronal and glial cell physiology as well as aspects of learning, memory,
and Alzheimer's disease, focusing on the involvement of L-type voltage-gated Ca 2+ channels. …

… of Cav1.2 and Cav1.3 containing channels complexes. The … DHPs efficiently inhibit Cav1.2
channels in vascular smooth … block of Cav1.2, and especially of Cav1.3, in neurons. Most …

… In the brain and heart, the β 2 AR forms a signaling complex with Ca v 1.2 that also
contains AC, the heterotrimeric guanine nucleotide–binding protein (G protein) G s , an A-kinase …

… signaling complex as might be prevalent in neurons (left) and cardiomyocytes (right). Ca v 1.2
is thought to mostly reside outside lipid rafts in neurons … predominant AKAP in neurons and …

… the L-type Ca 2+ channel that contributes to the rhythmic activity of adult DA neurons in the
… Finally, silencing of Cav1.3 in these cells confirmed that these currents are mediated via the …

… Much like in neurons, macromolecular protein complexes play key roles in modulating the
function of VSMCs and therefore have a major influence on vessel diameter. Control of VSMC …

… (LTCs) are mostly post-synaptic channels regulating neuronal … The Cav1 family consists of
four channel subtypes (Ca v 1.1 … The LTCs are complex voltage-gated, pore-forming, channels …

… regulator of neuronal Ca v 1 channels and ensures efficient Ca v 1.2 Ca 2+ signaling at … ,
we tested whether the two proteins form a complex in mouse brain. Antibodies that specifically …

… calcium channel complex found in skeletal muscle but is not found in neurons (Dolphin, 2016).
… Interestingly, young mice over-expressing Cav1.3 also show impairments in learning and …

… Ca v 1.3 channels are not only essential for cardiac … postsynaptically in neurons, where
they shape neuronal firing and … They affect neuronal activity in a complex manner. Through …