Channeling Vision: CaV1.4—A Critical Link in Retinal Signal Transmission

DM Waldner, NT Bech-Hansen… - BioMed research …, 2018 - Wiley Online Library
… on its role in transmission of visual signals from rod and cone … ) to the second-order retinal
neurons, and the pathological … a complex calcium current in photoreceptor terminals in vivo. …

[HTML][HTML] Rapid turnover of the cardiac L-Type CaV1. 2 channel by endocytic recycling regulates its cell surface availability

R Conrad, G Stölting, J Hendriks, G Ruello, D Kortzak… - Iscience, 2018 - cell.com
Calcium entry through Ca V 1.2 L-type calcium channels regulates cardiac contractility. Here,
we study the impact of exocytic and post-endocytic trafficking on cell surface channel

Activity-dependent facilitation of CaV1. 3 calcium channels promotes KCa3. 1 activation in hippocampal neurons

G Sahu, H Asmara, FX Zhang… - Journal of …, 2017 - Soc Neuroscience
L-type calcium channels play a key role in regulating the output of central neurons by providing
calcium … a long-duration calcium-dependent facilitation (L-CDF) of Ca V 1.3 channels that …

T-type calcium channels in neuropathic pain

E Bourinet, A Francois, S Laffray - Pain, 2016 - journals.lww.com
… Most neurons express multiple types of calcium channels, … or the calcium channel β subunits
in the case of Cav1 and … ) forming a molecular complex with the channel. These findings …

[HTML][HTML] The Contribution of L-Type Cav1.3 Channels to Retinal Light Responses

L Shi, JYA Chang, F Yu, ML Ko, GYP Ko - Frontiers in molecular …, 2017 - frontiersin.org
L-type voltage-gated calcium channels (LTCCs) regulate tonic neurotransmitter release
from sensory neurons … (LTCCs) are multi-subunit channel complexes composed of a pore-…

L-type calcium channels modulation by estradiol

NE Vega-Vela, D Osorio, M Avila-Rodriguez… - Molecular …, 2017 - Springer
Cav1.2 and Cav1.3 genes, two subtypes of L-type calcium … In neuronal cells, Cav1.2 and
Cav1.3 are often found in the … or modulation of the L-type calcium channel are complex and well-…

[HTML][HTML] Dynamic L-type CaV1. 2 channel trafficking facilitates CaV1. 2 clustering and cooperative gating

D Ghosh, M Nieves-Cintrón, S Tajada… - … Et Biophysica Acta (BBA …, 2018 - Elsevier
L-type Ca V 1.2 channels are key regulators of gene expression, cell excitability and muscle
contraction. Ca V 1.2 channels organize in clusters throughout the plasma membrane. This …

α‐Actinin‐1 promotes activity of the Ltype Ca2+ channel Cav1.2

M Turner, DE Anderson, P Bartels… - The EMBO …, 2020 - embopress.org
neuronal activity. Binding of α‐actinin to the IQ motif of Ca V 1.2 supports its surface localization
and postsynaptic targeting in neurons… EF3/4‐IQ complex contributing minimally if at all to …

[HTML][HTML] Modulation of L-type calcium channels in Alzheimer's disease: A potential therapeutic target

CA Crossley, V Rajani, Q Yuan - Computational and Structural …, 2023 - Elsevier
… flow of calcium into the neuron and as calcium ions flow into … Cav1.2 forms a unique signaling
complex with the β 2 -ARs … -ARs signaling can potently up-regulate LTCC channel activity. …

TGF-β1 protects trauma-injured murine cortical neurons by upregulating L-type calcium channel Cav1. 2 via the p38 pathway

Y Li, W Chen, H Deng, T Li, Z Liu, X Liu, Z Zhang… - Neuroscience, 2022 - Elsevier
… In summary, TGF-β1 increases trauma-injured murine cortical neuronal activity and inhibits
apoptosis by upregulating Cav1.2 channels via activating the p38 MAPK pathway. Therefore, …