Autophagy in osteoarthritis
H Jeon, GI Im - Connective Tissue Research, 2017 - Taylor & Francis
… in cartilage degeneration during osteoarthritis pathogenesis. … chondrocytes, while it induced
cell death by autophagy in OA … The link between autophagy and chondrocyte apoptosis …
cell death by autophagy in OA … The link between autophagy and chondrocyte apoptosis …
miR-4262 regulates chondrocyte viability, apoptosis, autophagy by targeting SIRT1 and activating PI3K/AKT/mTOR signaling pathway in rats with osteoarthritis
W Sun, Y Li, S Wei - Experimental and therapeutic …, 2018 - spandidos-publications.com
… were incubated with TdT reaction mix at 37C for 1 h. … cell death (33,34). Huang et al (35)
demonstrated that leptin was implicated in OA pathogenesis though promoting apoptosis and …
demonstrated that leptin was implicated in OA pathogenesis though promoting apoptosis and …
[HTML][HTML] MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling
C Cai, S Min, B Yan, W Liu, X Yang, L Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
… chondrocytes and could participate in OA pathogenesis. … attenuated cell growth, and induced
cell death and autophagy. In … cell proliferation and activation of apoptosis and autophagy in …
cell death and autophagy. In … cell proliferation and activation of apoptosis and autophagy in …
The role of apoptosis in the pathogenesis of osteoarthritis
SQ Xiao, M Cheng, L Wang, J Cao, L Fang… - International …, 2023 - Springer
… We also focused on apoptosis of articular chondrocytes in OA … that apoptosis is a form of
programmed cell death (PCD), … to the DISC with the combination of the adaptor protein FADD…
programmed cell death (PCD), … to the DISC with the combination of the adaptor protein FADD…
The role of autophagy in osteoarthritic cartilage
WC Kao, JC Chen, PC Liu, CC Lu, SY Lin, SC Chuang… - Biomolecules, 2022 - mdpi.com
… In histology, the main pathogenesis of OA is the terminal … that this cell death is like a mixture
of autophagy and classical … chondrocytes to show a different way of cellular demise [20]. …
of autophagy and classical … chondrocytes to show a different way of cellular demise [20]. …
The autophagic response to oxidative stress in osteoarthritic chondrocytes is deregulated
A Goutas, C Syrrou, I Papathanasiou, A Tsezou… - Free Radical Biology …, 2018 - Elsevier
… of cell death, referred to as type II death or autophagic death [… the presence of both apoptotic
as well as autophagic signals, … far ambiguous role of autophagy in OA pathogenesis, which …
as well as autophagic signals, … far ambiguous role of autophagy in OA pathogenesis, which …
Tetrahedral framework nucleic acid inhibits chondrocyte apoptosis and oxidative stress through activation of autophagy
… pathogenic process that is accompanied by excessive … Apoptotic cell death was documented
by the Cell Counting Kit-8 (… The mixture was preheated to 95 C (10 min) to fully denature …
by the Cell Counting Kit-8 (… The mixture was preheated to 95 C (10 min) to fully denature …
Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis
J Meng, H Du, H Lv, J Lu, J Li, J Yao - Frontiers in Immunology, 2023 - frontiersin.org
… However, its specific pathogenesis has not been clarified. This … autophagy and inhibiting
chondrocyte apoptosis in vitro. … trypsin (Solabio, China) at 37C, the mixture was incubated with …
chondrocyte apoptosis in vitro. … trypsin (Solabio, China) at 37C, the mixture was incubated with …
Extracellular vesicles and autophagy in osteoarthritis
T Gao, W Guo, M Chen, J Huang… - BioMed Research …, 2016 - Wiley Online Library
… the expression of autophagy genes can cause cell death [17], … Combined with the
phenomenon of the lack of an ACV … of chondrocyte dysfunctional autophagy in OA pathogenesis …
phenomenon of the lack of an ACV … of chondrocyte dysfunctional autophagy in OA pathogenesis …
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis
C Wen, L Lin, R Zou, F Lin, Y Liu - Cell Cycle, 2022 - Taylor & Francis
… in normal cartilage to avoid cell death caused by aging and … of chondrocyte autophagy
may be one of the pathogenesis … Chondrocytes were treated with IL-1β combined with PBS or …
may be one of the pathogenesis … Chondrocytes were treated with IL-1β combined with PBS or …