Pathological implication of protein post-translational modifications in cancer

S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
… The majority of the cell-surface receptors are transmembrane glycoproteins, such as …
receptor (EGFR), IGF receptor (IGFR), fibroblast growth factor receptor (FGFR), TGF β receptor (…

Prion protein as a toxic acceptor of amyloid-β oligomers

SA Purro, AJ Nicoll, J Collinge - Biological psychiatry, 2018 - Elsevier
… In receptor binding terminology, both receptor and acceptor … More research is needed to
confirm the consequences of Aβ … According to this study, cellular PrP (PrP C ) is not required for …

[HTML][HTML] Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

CJ Holland, RM Crean, JM Pentier… - … Journal of clinical …, 2020 - Am Soc Clin Investig
… via selective T cell receptor (TCR) recognition of pHLA, enabling T cell triggering … implications
for the underlying rules that determine pHLA discrimination and identify key considerations

[PDF][PDF] Alcoholic Myopathy: Pathophysiologic Mechanisms and Clinical Implications.

L Simon, SE Jolley, PE Molina - uniad.org.br
… Finally, there are conflicting data regarding the use of selective androgen receptor
acceptors via reduction and oxidation. The ETC serves as the most productive pathway of cellular

[HTML][HTML] Advances in deubiquitinating enzyme inhibition and applications in cancer therapeutics

AM Antao, A Tyagi, KS Kim, S Ramakrishna - Cancers, 2020 - mdpi.com
… and DUBs that potentially have clinical implications in cancer, … We also discuss the clinical
applications of promising DUB … for the delivery of membrane receptors from the cell surface to …

Enzymes in metabolic anticancer therapy

M Maggi, C Scotti - … Enzymes: Function and Clinical Implications, 2019 - Springer
… that cell metabolism is rewired during tumorigenesis and metastasis as a consequence of …
group from the glutamine donor to the aspartate acceptor to form asparagine and glutamate. In …

[HTML][HTML] A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155

B Husain, SR Ramani, E Chiang, I Lehoux… - Molecular & Cellular …, 2019 - ASBMB
… The biotinylated query protein was incubated with the acceptor beads for 1 h at room … to
the 384-well plates containing the acceptor bead/STM receptor using a Tempest liquid handler (…

Shedding light on the cell biology of extracellular vesicles

G Van Niel, G d'Angelo, G Raposo - Nature reviews Molecular cell …, 2018 - nature.com
… many different cell types, and its implications in intercellular … surface of extracellular vesicles
and receptors at the plasma … and molecular basis for the specific targeting to acceptor cells is …

[HTML][HTML] ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretation

J Malcikova, E Tausch, D Rossi, LA Sutton, T Soussi… - Leukemia, 2018 - nature.com
… , ie, inhibitors of B-cell receptor (BcR) signaling and anti-… a splice donor and a splice acceptor
site, sequencing of +2/−… ; (iii) conclusion: clinical consequence of the variant and summary …

Oxidative stress, consequences and ROS mediated cellular signaling in rheumatoid arthritis

AR Phull, B Nasir, I ul Haq, SJ Kim - Chemico-biological interactions, 2018 - Elsevier
acceptor of electron pair to frame H 2 O 2 equal for catalysis of every disulphide bond synthesis,
giving a ROS flux in this cell … Binding of cell death receptors with their ligands trigger the …