[HTML][HTML] Developing new therapeutic approaches for treating infections caused by multi-drug resistant Acinetobacter baumannii: Acinetobacter baumannii therapeutics

P Gallagher, S Baker - Journal of Infection, 2020 - Elsevier
… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … baumannii infections, there is
mounting pressure to find new … While A.baumannii remains a major public health challenge

… Targeted Therapy of Infection-Related Ventilator-Associated Complications (IVACs) Caused by Pseudomonas aeruginosa and Acinetobacter baumannii in Critically …

M Gatti, B Viaggi, GM Rossolini, F Pea, P Viale - Antibiotics, 2021 - mdpi.com
identification in less than 40% of patients with clinically diagnosed IVACs [12]. This has
traditionally made challenging … ; (b) to appropriately place novel antimicrobial agents in lack of …

Acinetobacter baumannii Resistance: A Real Challenge for Clinicians

…, LA Padró Alonzo, A Rivera Reséndiz… - Antibiotics, 2020 - mdpi.com
baumannii, with the objective of identifying the most … that effectively escape the effects
of antibacterial drugs [16]. … such as Pseudomonas aeruginosa, Acinetobacter baumannii, …

A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.

JA Goldberg, V Kumar, EJ Spencer, D Hoyer… - European Journal of …, 2021 - Elsevier
… Multidrug resistance to antibiotics is a challenging global … , Pseudomonas aeruginosa,
Acinetobacter baumannii) present … initial attributes of an antibacterial agent effective against Gram-…

Recent trends and challenges to overcome Pseudomonas aeruginosa infections

A Ammazzalorso, A Granese… - Expert Opinion on …, 2024 - Taylor & Francis
… To develop new efficacious antimicrobial agents, it is necessary to know the pathways …
mechanisms of virulence and antibacterial resistance is crucial to identify new biological targets. …

Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections

DRA Sanya, D Onésime, G Vizzarro, N Jacquier - BMC microbiology, 2023 - Springer
… Bacterial biofilms still remain a challenge to the healthcare system due to their resilience
against antimicrobial agents and immune system. Moreover, mechanisms involved in biofilm …

New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review

AR Losito, F Raffaelli, P Del Giacomo, M Tumbarello - Antibiotics, 2022 - mdpi.com
… It is intrinsically resistant to many antimicrobial agents and additional acquired … to
ceftolozane-tazobactam has been identified in P. … aeruginosa, in challenging clinical situations …

Multidrug Resistant Acinetobacter baumannii: Resistance by Any Other Name Would Still be Hard to Treat

DA Butler, M Biagi, X Tan, S Qasmieh… - Current infectious …, 2019 - Springer
… Finally, new antimicrobial agents such as eravacycline and … of this challenging pathogen,
antimicrobial resistant AB (MDR, DTR, … Enterobacteriaceae and Pseudomonas aeruginosa and …

Antimicrobial-resistant Pseudomonas aeruginosa and Acinetobacter baumannii from patients with hospital-acquired or ventilator-associated pneumonia in Vietnam

DJ Biedenbach, PT Giao, PH Van, NSM Tuyet… - Clinical Therapeutics, 2016 - Elsevier
antimicrobial agents used to treat A baumannii and P aeruginosa infections in this country. …
A central laboratory verified identification of the isolates and performed susceptibility testing …

Urinary tract infection by Acinetobacter baumannii and Pseudomonas aeruginosa: evolution of antimicrobial resistance and therapeutic alternatives

G Jiménez-Guerra, V Heras-Cañas… - Journal of medical …, 2018 - microbiologyresearch.org
… to identify microorganisms and evaluate susceptibility to the following … challenge.
Cephalosporins and quinolones have long been extensively administered as the empirical treatment