… Rotavirus vaccines remain an effective tool against diarrheal … severe rotavirus AGE for children
<5 years in Nicaragua was … and impact of rotavirus vaccines a decade after their licensure …

… the residual cases of RVA diarrhea in the post-vaccination period… , results indicate that in
Nicaragua (where the strategy with … -1-like change trend, the strain changes were not consistent …

… diarrhea in children under five years old is rotavirus [2]. In fact… result but during the second
year of follow up (efficacy 39%; … RV5 in children from Nicaragua [34] showed similar vaccine …

… just one year after the introduction of the vaccine, Nicaragua reported a significant decrease
in diarrhea-… Another focus to improve vaccine performance is the development of injectable …

… Rotavirus is a leading cause of acute diarrhea in children … expect changes in seasonal
patterns after universal vaccine … changes in rotavirus incidence associated with vaccination. For …

… rotavirus prevalence in moderate-to-severe diarrhea cases to WHO estimates of the number
of diarrhea deaths in children[… These developments in the rotavirus vaccine marketplace and …

… in diarrhea mortality after rotavirus vaccine implementation. In … Third, while changes in the
proportion of severe diarrhea … the decline in incidence of rotavirus disease following vaccine …

… The change in rotavirus prevalence was evaluated using … was the commonest cause of
childhood diarrhoea worldwide … calendar year prior to rotavirus vaccine introduction, incidence …

… change in the clinical profile of children being treated with acute diarrhoea after the introduction
of the rotavirus vaccine … Nicaragua they observed a 40% lower incidence rate of watery …

… The rotavirus vaccine was first introduced in 2006, and … In Nicaragua, it is possible that the
lack of a booster dose after the … that diarrhea visits actually increased in the vaccine years, …