Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia
… proliferation, and prosurvival characteristics of AML blasts may … a downstream target of
CEBPA [59] and SP1 [60, 61], key hub … of gene transcription either through direct DNA binding, or …
CEBPA [59] and SP1 [60, 61], key hub … of gene transcription either through direct DNA binding, or …
S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma
M Tochimoto, Y Oguri, M Hashimura, R Konno… - Laboratory …, 2020 - nature.com
… for functional analysis of S100A4 gene used in this study. … co-operates with factors binding
minisatellite DNA sequences… Metastasis-associated Mts1 (S100A$) protein modulates protein …
minisatellite DNA sequences… Metastasis-associated Mts1 (S100A$) protein modulates protein …
[HTML][HTML] Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression
G Mudduluru, K Ilm, S Fuchs, U Stein - Oncotarget, 2017 - ncbi.nlm.nih.gov
… by SP1, AP1 and kappa recognition component (KRC) … of the important metastasis-associated
gene S100A4 by miRs … its functional impact on metastasis-associated characteristics like …
gene S100A4 by miRs … its functional impact on metastasis-associated characteristics like …
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins
Q Al-Ismaeel, CP Neal, H Al-Mahmoodi… - British Journal of …, 2019 - nature.com
… proteins, most of which exert intra- and extracellular functions. In the human genome, 17 …
analysis of S100 transcriptomes in both cell lines. ZEB1-induced expression of only two genes, …
analysis of S100 transcriptomes in both cell lines. ZEB1-induced expression of only two genes, …
Characterization of UHRF2 (RNF107) as a novel sensor for DNA ICLs in the Fanconi Anemia Pathway
A Motnenko - 2017 - ora.ox.ac.uk
… characterized as an FA gene it must be found to be mutated in an FA patient and complementation
of this gene … preferentially bind ICLs in vitro, which may be indicative of its function in …
of this gene … preferentially bind ICLs in vitro, which may be indicative of its function in …
Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
A Motnenko, CC Liang, D Yang, D Lopez-Martinez… - PLoS …, 2018 - journals.plos.org
… To further characterize the interaction between these two proteins we turned to in vitro co-…
this translates to a functional genetic relationship between the two genes. We depleted UHRF1 …
this translates to a functional genetic relationship between the two genes. We depleted UHRF1 …