… hepcidin. Our study focused on the model DTHFPI-NH 2 hexapeptide reflecting the N-terminal
motif of mature hepcidin… Based on these results we propose that hepcidin could exist as Cu…

… (5R-hepcidin). … hepcidin we demonstrated that hepcidin can compete for Cd(II) ions with
metallothionein-2, a cellular cadmium target. This study enabled us to conclude that hepcidin …

… To our knowledge, none of the materials used for hepcidin analysis have been characterized
in this respect, yet. Even simple (non-chiral) amino acid analysis can be very useful for the …

… Hepcidin is an iron regulatory hormone that does not bind iron directly. Instead, its mature
25… The Cu(II)-hepcidin complex was previously studied, but due to poor solubility and difficult …

… and mechanistic properties of ill-characterized metalloproteins at … hepcidin without evidence
of transition metal binding [64]. Similarly, production of C-terminal histidine-tagged hepcidin …

… systems are the most well characterized to date and are … hepcidin to inhibit iron transport
into the bloodstream [36]. … The hCP heterodimer has two transition metal-binding sites …

… We demonstrate that Fpn and Heph co-localize, and FRET analysis indicated that the two
proteins form an iron-efflux complex. In contrast, none of the full-length, cellular APP proteins …

… We tested the influence of vial material and sample injection solution on the hepcidin
concentration, using LC-MS/MS analysis employing TFA-based solvents. The influence of the …

… During infection, the small peptide hormone hepcidin is secreted from the liver (12-14). It …
We next tested whether calprotectin association with Bb required transition metal binding sites …

… NMC–Cu 2+ complexes were further characterized by pH titration. The stoichiometries
and overall stability constants (log β pqr ) thus determined, which are shown in Table 2, were …