[HTML][HTML] Allogeneic hemopoietic stem cell transplantation for myelofibrosis: 2021

A Bacigalupo, I Innocenti, E Rossi, F Sora… - Frontiers in …, 2021 - frontiersin.org
… current status of allogeneic hemopoietic stem cell transplants (… size, as predictors of transplant
outcome. The choice of a … monitoring the disease after HSCT with donor chimerism, driver …

… on outcomes of mixed chimerism of bone marrow CD34+ sorted cells after matched or haploidentical allogeneic stem cell transplantation for myeloid malignancies

Y Le Bris, D Costes, R Bourgade, T Guillaume… - … Marrow Transplantation, 2022 - nature.com
… , BM-CD34 + SC mixed chimerism appears here of high predictive value for relapse … -transplant
relapse. Moreover, full CD34 chimerism is a good indicator of successful hematopoietic

Incomplete chimerism following myeloablative and anti-thymocyte globulin-conditioned hematopoietic cell transplantation is a risk factor for relapse and chronic graft …

RA Khanolkar, G Tripathi, P Dharmani-Khan, R Dabas… - Cytotherapy, 2022 - Elsevier
… by chimerism status. The median time to chimerism assessment was 84 days post-transplant
(… of ATG AUC, these clinical factors may be useful surrogate predictors of T-cell chimerism. …

[HTML][HTML] Clinical utility of quantitative PCR for chimerism and engraftment monitoring after allogeneic stem cell transplantation for hematologic malignancies

M Ahci, K Stempelmann, U Buttkereit, P Crivello… - … Marrow Transplantation, 2017 - Elsevier
… A status of persistent mixed chimerism (PMC) of blood cells … kinetics are relevant for their
interpretation, relapse prediction … qPCR chimerism was also useful to monitor the efficacy and …

Prediction, management, and prognosis of mixed chimerism after hematopoietic stem cell transplantation in transfusion‐dependent pediatric thalassemia patients

H Chen, X Li, L Zhan, J Fang, K Huang… - … Transplantation, 2020 - Wiley Online Library
… has been used to prevent relapse after HSCT in leukemia … We gratefully acknowledge the
valuable cooperation of Center … Company for detection of chimerism status for our patients. We …

[HTML][HTML] Post-transplantation day+ 100 minimal residual disease detection rather than mixed chimerism predicts relapses after allogeneic stem cell transplantation for …

E Klyuchnikov, A Badbaran, R Massoud… - Transplantation and …, 2022 - Elsevier
… may have greater predictive value for relapse than mixed chimerism (MC) in … stem cell
transplantation, followed closely by MFC-MRD. In contrast, chimerism status had limited predictive

[HTML][HTML] … Sequencing for Detection of Engraftment and Early Disease Relapse in Allogeneic Hematopoietic Cell Transplantation and an Overview of NGS Chimerism …

A Liacini, G Tripathi, A McCollick, C Gravante… - International Journal of …, 2023 - mdpi.com
… Maintenance of complete chimerism status indicates … and metabolomics as predictive
biomarkers of patient response … The results represent a good correlation of the expected …

[HTML][HTML] Monitoring measurable residual disease and chimerism in patients with JAK2 V617F-positive myelofibrosis after allogeneic hematopoietic cell transplantation

JM Lee, A Ahn, EJ Min, SE Lee, M Kim, Y Kim - Blood Cancer Journal, 2023 - nature.com
… molecular markers might prevent overt relapse, possibly through the strong graft-versus-tumor
effect of MF, and that the MC status provides a useful indicator for additional interventions […

The mythological chimera and new era of relapse prediction post-transplant

SO Ciurea, A Kothari, S Sana, MM Al Malki - Blood Reviews, 2023 - Elsevier
Allogeneic hemopoietic stem cell transplantation is the … of patients relapsing based on
disease risk and status at transplant. … chimerism has comparable sensitivity to RT-PCR with good

[HTML][HTML] Chimerism monitoring techniques after hematopoietic stem cell transplantation: an overview of the last 15 years of innovations

P Tozzo, A Delicati, R Zambello, L Caenazzo - Diagnostics, 2021 - mdpi.com
… the status of the chimerism in a subset of hematopoietic cells, … [12], dPCR can be used
as a surrogate indicator of MRD in … useful for chimerism monitoring in the case of multiple-donor …