The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience

J Loke, R Malladi, P Moss… - British Journal of …, 2020 - Wiley Online Library
… with good risk cytogenetics and a low predicted risk of relapseChimerism status will be
a critical determinant of immune … as the most important predictor of relapse. On the basis of …

[HTML][HTML] … of hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism in allogeneic hematopoietic cell transplantation: a report on …

MA Kharfan-Dabaja, A Kumar, E Ayala, M Aljurf… - Transplantation and …, 2021 - Elsevier
chimerism trajectory occur in the setting of disease relapse/… quantifying donor chimerism
levels to confirm graft failure (… factors, such as patient functional status and disease-specific …

The consensus on the monitoring, treatment, and prevention of leukemia relapse after allogeneic hematopoietic stem cell transplantation in China

Y Wang, H Chen, J Chen, M Han, JD Hu, J Hu… - Cancer Letters, 2018 - Elsevier
… from complete donor chimerism to mixed donor chimerism of sex … status after the second
month post-HSCT was a predictor of CIR. … , disease status, and donor intention can be helpful in …

Multivariate Analysis of Immune Reconstitution and Relapse Risk Scoring in Children Receiving Allogeneic Stem Cell Transplantation for Acute Leukemias

M Spadea, F Saglio, SI Tripodi, M Menconi… - Transplantation …, 2021 - journals.lww.com
… These factors are strictly interconnected and valuable … the previous ones, spreading to
relapse prediction. Indeed, we … regimen, disease type and status, negative history of steroid …

Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation

J Duque-Afonso, M Waterhouse, D Pfeifer, M Follo… - Clinical …, 2018 - Elsevier
… cfDNA chimerism status in patients with complications after … is not possible to establish the
predictive value of recipient cfDNA for … cfDNA kinetics after alloHSCT might be clinically useful. …

Risk factors predicting graft-versus-host disease and relapse-free survival after allogeneic hematopoietic stem cell transplantation in relapsed or refractory non …

YW Jeon, S Yoon, GJ Min, SS Park, S Park… - Annals of …, 2019 - Springer
… In conclusion, these results suggest that GRFS is also a useful endpoint to assess transplant
… All patients were evaluable for hematopoietic recovery and chimerism status. Patients …

Ultrasensitive chimerism enhances measurable residual disease testing after allogeneic hematopoietic cell transplantation

SB Kanaan, F Urselli, JP Radich, JL Nelson - Blood Advances, 2023 - ashpublications.org
… in predicting relapse when pre-transplant MRD was known but not necessarily so when
disease status at transplant was … status is a useful predictor of relapse after allogeneic stem

Incomplete chimerism following myeloablative and anti-thymocyte globulin-conditioned hematopoietic cell transplantation is a risk factor for relapse and chronic graft …

RA Khanolkar, G Tripathi, P Dharmani-Khan, R Dabas… - Cytotherapy, 2022 - Elsevier
… by chimerism status. The median time to chimerism assessment was 84 days post-transplant
(… of ATG AUC, these clinical factors may be useful surrogate predictors of T-cell chimerism. …

Assessment of chimerism and immunomodulation to prevent post-transplantation relapse in childhood acute myeloblastic leukemia: is it the right approach?

E Cousin, E Oger, JH Dalle, Y Bertrand… - Pediatric Hematology …, 2020 - Taylor & Francis
… first allogenic hematopoietic stem-cell transplantation (allo-… after one, three and six months
to assess the disease status. In … highlighted the excellent negative predictive value of CC, …

Survival, nonrelapse mortality, and relapse-related mortality after allogeneic hematopoietic cell transplantation: comparing 2003–2007 versus 2013–2017 cohorts

GB McDonald, BM Sandmaier, M Mielcarek… - Annals of internal …, 2020 - acpjournals.org
… disease recurrence—in fact, we saw a reduction, even after … such factors as age, disease
status, and comorbidity score in our … molecular and genomic markers predictive of outcomes in …