Chondroitin sulfate-rich extract of skate cartilage attenuates lipopolysaccharide-induced liver damage in mice

YO Song, M Kim, M Woo, JM Baek, KH Kang, SH Kim… - Marine Drugs, 2017 - mdpi.com
… The protective effects of a chondroitin sulfate-rich extract (CSE) from skate cartilage against
… mechanism of action was compared with that of chondroitin sulfate (CS) from shark cartilage. …

Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation

J Yamada, S Maeda, M Soya, H Nishida… - The Journal of …, 2022 - Elsevier
… We examined whether the administration of LPS and SES might affect the densities of
astrocytes, NSCs, and early TAPs in the subgranular zone of the dentate gyrus (Fig. 3). Quadruple …

[HTML][HTML] Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules

TV Stabler, Z Huang, E Montell, J Vergés… - Osteoarthritis and …, 2017 - Elsevier
… To evaluate the anti-inflammatory mechanism of action of Chondroitin Sulphate (CS). … -related
inflammation. CS works upstream of the inflammasome by inhibiting activation of NF-κB …

Inhibitory effects of skate cartilage chondroitin sulfate-rich extract on the production of inflammatory mediators and ROS in lipopolysaccharide-treated murine …

M Woo, DH Kwon, YH Choi, JS Noh - In Vitro Cellular & Developmental …, 2020 - Springer
… Our results are in agreement with other studies that soluble chondroitin-6-sulfate from
shark cartilage is a potent inhibitor of NO activity (Tan and Tabata 2014). Similarly, other …

Fucosylated Chondroitin Sulfate against Parkinson's Disease through Inhibiting Inflammation Induced by Gut Dysbiosis

Y Liu, X Liu, Q Ye, Y Wang, J Zhang, S Lin… - Journal of Agricultural …, 2022 - ACS Publications
astrocyte marker GFAP and the microglia marker Iba-1, we were able to identify the population
of astrocytes … to block the proinflammatory factors that lipopolysaccharide induced in BV2 …

Astrocytic GAP43 induced by the TLR4/NF-κB/STAT3 axis attenuates astrogliosis-mediated microglial activation and neurotoxicity

CC Hung, CH Lin, H Chang, CY Wang… - Journal of …, 2016 - Soc Neuroscience
… In this study, we show that GAP43 expression in primary cultured rat astrocytes as induced
by LPS plays beneficial roles in immune modulation and neuronal survival and plasticity …

Chondroitin and glucosamine sulphate reduced proinflammatory molecules in the DRG and improved axonal function of injured sciatic nerve of rats

OF Olaseinde, BV Owoyele - Scientific reports, 2022 - nature.com
… of glucosamine sulphate (GS) (240 mg/kg) and chondroitin sulphate (CS) (900 mg/kg) in
chronic constriction injury (CCI)-induced neuropathy in rats. Forty-two Wistar rats were …

Intervention effects of low-molecular-weight chondroitin sulfate from the nasal cartilage of yellow cattle on lipopolysaccharide-induced behavioral disorders: regulation …

Y Deng, Q Li, J Song, R Guo, T Ma, Z Liu, Q Liu - Frontiers in Nutrition, 2024 - frontiersin.org
Chondroitin sulfate (CS) is a sulfated linear polysaccharide with different functional activities,
including antioxidant, anti-inflammatory, … Two low-molecular-weight chondroitin sulfates (…

The therapeutic potential of chondroitin sulfate in Aspergillus fumigatus keratitis

J Luan, X Peng, J Lin, Y Zhang, X Tian, L Zhan… - Molecular …, 2022 - Elsevier
… CS treatment reduced the expression of pro-inflammatory cytokines (TNF-α, IL-1β, etc.) in
rat with experimental models of acute inflammation of the hind limb and degenerative-…

Chondroprotectors as modulators of neuroinflammation

IY Torshin, OA Gromova… - Neurology …, 2023 - nnp.ima-press.net
Inhibition of astrocytic differentiation of transplanted neural stem cells by chondroitin
sulfate … after ischemic stroke in normotensive and hypertensive rats. Exp Neurol. 2015 Mar;265:142-…