… -level laser therapy on the proliferative, apoptosis modulation, and oxi-inflammatory markers of premature-senescent hydrogen peroxide-induced dermal fibroblasts

DR Maldaner, VF Azzolin, F Barbisan… - Lasers in Medical …, 2019 - Springer
… Again, extrinsic factors can induce pro-oxidative states … with existence of chronic inflammatory
states that present an … exposed, LLLT action on fibroblast was more pronounced, since this …

Mitochondrial and nuclear DNA oxidative damage in physiological and pathological aging

M Kowalska, T Piekut, M Prendecki, A Sodel… - DNA and cell …, 2020 - liebertpub.com
… of ROS associated with mitochondrial dysfunction amount to a “… and mitochondrial dysfunction.
Therefore, overproduction of ROS and mitochondrial abnormalities, together with chronic

Implications of oxidative stress and potential role of mitochondrial dysfunction in COVID-19: therapeutic effects of vitamin D

N de Las Heras, VM Martín Giménez, L Ferder… - Antioxidants, 2020 - mdpi.com
… In fact, the leukemia virus infection on fibroblasts resulted in a … of cardiac dysfunction induced
by chronic immobilization … a pro-oxidative state associated with mitochondrial dysfunction […

Mitochondria and cellular redox state on the route from ageing to Alzheimer's disease

G Abate, M Vezzoli, M Sandri… - Mechanisms of Ageing …, 2020 - Elsevier
chronic age-related diseases, including neurodegenerative … environment to one with a
pro-oxidative profile would result in … described mitochondrial dysfunction as a prominent and early …

[PDF][PDF] Mitochondrial dysfunction and biological therapy: a new look at rheumatoid arthritis

T Kostova, V Mihaylova, R Karalilova… - Rheumatology …, 2022 - researchgate.net
… are associated with more pronounced hypoxia in the joint [9]. … and mitochondrial proteins
reflect mitochondrial dysfunctionsevere and prolonged inflammation in the joints of mice [13]. …

Mitochondrial dysfunction in lung ageing and disease

SM Cloonan, K Kim, P Esteves, T Trian… - European Respiratory …, 2020 - Eur Respiratory Soc
… become dysfunctional with ageing and in acute and chronic lung … This leads to chronic
bacterial airway infection, prominent … repressed in IPF fibroblasts and in fibroblasts isolated from …

PERK-mediated unfolded protein response activation and oxidative stress in PARK20 fibroblasts

G Amodio, O Moltedo, D Fasano, L Zerillo… - Frontiers in …, 2019 - frontiersin.org
… that PARK20 fibroblasts exhibited pronounced oxidative stress. … chronic ER stress can
even potentiate MAMs altering the … , OS induction and mitochondrial dysfunction. Thus, these …

Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart

D Bou-Teen, N Kaludercic, D Weissman… - Free Radical Biology …, 2021 - Elsevier
… and increased pro-oxidative status, largely involve mitochondria and … pathways in cardiac
fibroblasts and modulate matrix … the role of chronic ROS exposure and mitochondrial ROS in …

[HTML][HTML] Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds

M Wlaschek, K Singh, A Sindrilaru, D Crisan… - Free Radical Biology …, 2019 - Elsevier
pro-oxidative and pro-inflammatory M1 activation state in … unit suffering from severe disorders
including multiple trauma, … In senescent cells, lipofuscin is visible by autofluorescence. …

[HTML][HTML] Happily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

A Höhn, D Weber, T Jung, C Ott, M Hugo, B Kochlik… - Redox biology, 2017 - Elsevier
… Thus, mitochondria are considered the most prominent … proteins, a marker for severe and
chronic oxidative stress, were … such as: human dermal fibroblasts in tissue culture, human lens, …