Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism

S Badawy, YQ Yang, Y Liu, MA Marawan… - Critical Reviews in …, 2021 - Taylor & Francis
… Approach to systematic review This review article provides an overview of the basic toxicology
… levels are thought to be the possible mechanisms of CIP neurotoxicity (Ilgin et al. Citation…

An examination of the effect of rutin against neurotoxicity induced by ciprofloxacin antibiotic in wistar rats

AJ Al-Naely, HA Al-Hamadawi… - Archives of Razi …, 2022 - archrazi.areeo.ac.ir
… Almutairi, Alanazi ( 34 ) demonstrated that Rutin has beneficial effects and can reduce
cisplatin medicine neurotoxicity with possible mechanisms by its antioxidant nature. On the other …

Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP

MM Khalaf, HM Mahmoud, MA Kandeil… - Drug and Chemical …, 2024 - Taylor & Francis
evaluation of fumaric acid’s role in the control of p190-RhoGTP in a rat model of
ciprofloxacin-induced … putative neuroprotective mechanism of fumaric acid against …

Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4

A Salama, HAAH Mahmoud, MA Kandeil… - Immunopharmacology …, 2021 - Taylor & Francis
… The aim of the current study was to evaluate camphor possible neuroprotective effect against
… to be the possible mechanisms of ciprofloxacin-associated neurotoxicity and inflammation […

Protective Influence of Phyllanthus Muellarianus on Ciprofloxacin-Induced Neurotoxicity in Male Rats

OB Ibitoye, NO Aliyu, TO Ajiboye - Journal of Dietary Supplements, 2020 - Taylor & Francis
… leaf extract of Phyllanthus muellarianus on ciprofloxacin neurotoxicity in male rats. Control
rats (… muellarianus reversed ciprofloxacin-induced neurotoxicity by restoring ciprofloxacin-…

Long-term toxicity of fluoroquinolones: a comprehensive review

NHA Hussen, SH Qadir, HS Rahman… - Drug and Chemical …, 2024 - Taylor & Francis
… Therefore, we provide a summary of the molecular mechanisms responsible for the long-…
These results show that the association between structures of neurotoxicity and FQs is not well-…

Neurobehavioral impairments in ciprofloxacin-treated osteoarthritic adult rats.

G Kékesi, E Ducza, H Gálity, A Büki… - Clinical …, 2023 - search.ebscohost.com
… Fluoroquinoloneinduced neurotoxic adverse events have been reported in a few case …
preclinical studies have examined the mechanisms underlying the observed psychogenic effects. …

Synergistic effect of spermidine and ciprofloxacin against Alzheimer's disease in male rat via ferroptosis modulation

MAM Youssef, TM Mohamed, AA Bakry… - International Journal of …, 2024 - Elsevier
… This study investigated AD-related biomarkers like neurotoxic amyloid beta (Aβ), arginase
I, and … [68] elucidated the underlying mechanism, revealing SPD's ability to target histone …

Depressive and other adverse CNS effects of fluoroquinolones

P Wierzbiński, J Hubska, M Henzler, B Kucharski… - Pharmaceuticals, 2023 - mdpi.com
… studies were further evaluated for key terms and relevance to the aims of the review. After …
Finally, further research is needed to confirm the underlying mechanisms of fluoroquinolone-…

Relationship between fluoroquinolone structure and neurotoxicity revealed by zebrafish neurobehavior

C Xiao, Y Han, Y Liu, J Zhang, C Hu - Chemical Research in …, 2018 - ACS Publications
… , and the latter was used for neurotoxicity assessment. Lethal concentration results from …
We used the IC/MC to evaluate absorption capacity, and a higher IC/MC suggests that the …